AibGenesis™ Rabbit Anti-LTK Recombinant Antibody (VS-0426-FY891)
CAT#: VS-0426-FY891
VS-0426-FY891 is a Rabbit IgG targeting Leukocyte Tyrosine Kinase (LTK), developed using our AI-powered antibody discovery platform. Validated for WB and IHC in Human and Rat species, this affinity-purified antibody offers robust performance. It provides a valuable tool for studying receptor tyrosine kinase signaling and its implications in autoimmune and neoplastic diseases.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59545/1417_A10_1_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (HEL, NB-4, RH-30, THP-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000062524-LTK
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| Sub Cat | Species Reactivity | Clone | Applications | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS-0426-FY115 | Human, Rat | AibG-Rb-LT115 | WB, IHC | ||||||
| VS-0426-FY116 | Human | AibG-Rb-LT116 | WB, IHC, IF-P |
More Infomation
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- LTK
- Conjugate
- Unconjugated, Biotin and FITC are available.
- Related Disease
- Rosai-Dorfman Disease
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Target
- Alternative Names
- TYK1
- Gene ID
- 4058
- UniProt ID
- P29376
- Long Name
- leukocyte receptor tyrosine kinase
- Sequence Similarities
- Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Phosphorylated at tyrosine residues by autocatalysis, which activates kinase activity. (P29376-LTK_HUMAN)
Glycosylation at Asn257, Asn380, and Asn412 (NX_P29376 [NX_P29376-1])
Modification sites at PhosphoSitePlus (P29376)
Glycosylation from GlyGen (P29376) 3 sites
- Protein Refseq
- XP_011519859.1; XP_024305687.2; XP_047288455.1; XP_047288456.1; XP_047288457.1
- Function
- Receptor with a tyrosine-protein kinase activity (PubMed:10445845, PubMed:20548102, PubMed:30061385).
Following activation by ALKAL1 or ALKAL2 ligands at the cell surface, transduces an extracellular signal into an intracellular response (PubMed:30061385, PubMed:34646012).
Ligand-binding to the extracellular domain induces tyrosine kinase activation, leading to activation of the mitogen-activated protein kinase (MAPK) pathway.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| TAB-0712CL | Anti-Human LTK Recombinant Antibody (FAM150B) | ELISA, FuncS, FC, WB, Activ, IP, IHC | Human antibody |
| CAT | Product Name | Application | Type |
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| TAB-0711CL-S(P) | Anti-Human LTK Recombinant Antibody scFv Fragment (FAM150A) | ELISA, FC | Human antibody |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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