AbPlus™ Anti-MCAM Magnetic Beads (ScFv7)
CAT#: VS-0424-XY185
The AbPlus Anti-MCAM Magnetic Beads (ScFv7) is an innovative affinity resin which is bound with anti-MCAM specific antibody (ScFv7). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of MCAM protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2147/if_selected.jpg
Normal Tissue
Figure 2 Soft tissue
Fibroblasts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8848/24112_B_2_7.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Neuronal cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8848/24112_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8848/24112_A_8_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8848/24112_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Peritubular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Low Intensity: Weak Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8848/24112_A_4_6.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (HUVEC TERT2, TIME, WM-115)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076706-MCAM
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-MCAM specific antibody (ScFv7)
- Target
- MCAM
- Target Species
- Human
- Antibody Clone
- ScFv7
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. MCAM could be an adhesion molecule active in neural crest cells during embryonic development.
- Alternative Names
- CD146; MUC18
- Gene ID
- 4162
- UniProt ID
- P43121
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "MCAM"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-516CL | Anti-Human MCAM Recombinant Antibody (ABX-MA1) | WB, FuncS | Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-441MZ | Mouse Anti-MCAM Recombinant Antibody (TAB-441MZ) | FC, FuncS | Mouse IgG1 |
| TAB-441MZ-S(P) | Mouse Anti-MCAM Recombinant Antibody; scFv Fragment (TAB-441MZ-S(P)) | FC, WB, IHC | Mouse scFv |
| TAB-441MZ-F(E) | Mouse Anti-MCAM Recombinant Antibody; Fab Fragment (TAB-441MZ-F(E)) | FC, WB, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-442MZ | Human Anti-MCAM Recombinant Antibody (TAB-442MZ) | FC, WB, IHC | Chimeric (Mouse/Human) IgG1 |
| TAB-443MZ | Human Anti-MCAM Recombinant Antibody (TAB-443MZ) | FC, WB, IHC | Chimeric (Mouse/Human) IgG3 |
| TAB-442MZ-S(P) | Human Anti-MCAM Recombinant Antibody; scFv Fragment (TAB-442MZ-S(P)) | FC, WB, IHC | Human scFv |
| TAB-442MZ-F(E) | Human Anti-MCAM Recombinant Antibody; Fab Fragment (TAB-442MZ-F(E)) | FC, WB, IHC | Chimeric (Mouse/Human) Fab |
| TAB-443MZ-F(E) | Human Anti-MCAM Recombinant Antibody; Fab Fragment (TAB-443MZ-F(E)) | FC, WB, IHC | Chimeric (Mouse/Human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-444MZ | Anti-Human MCAM Recombinant Antibody (TAB-444MZ) | ELISA | Humanized antibody |
| TAB-444MZ-S(P) | Anti-Human MCAM Recombinant Antibody scFv Fragment (TAB-444MZ-S(P)) | ELISA | Humanized antibody |
| TAB-444MZ-F(E) | Anti-Human MCAM Recombinant Antibody Fab Fragment (TAB-444MZ-F(E)) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2188 | Hi-Affi™ Recombinant Rabbit Anti-MCAM Monoclonal Antibody (DS2188AB) | ICC, IF, IHC-Fr, WB, IP, IHC-P, ICC, FC | IgG |
| MOR-4644 | Hi-Affi™ Recombinant Rabbit Anti-MCAM Monoclonal Antibody (TH157DS) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0013-CN | Human Anti-MCAM Recombinant Antibody (clone ScFv7) | IP, FC | Human IgG1 |
| HPAB-0014-CN | Human Anti-MCAM Recombinant Antibody (clone ScFv9) | IP, FC | Human IgG1, κ |
| HPAB-0493LY | Human Anti-MCAM Recombinant Antibody (clone H5L0) | ELISA | Humanized IgG1 |
| HPAB-0494LY | Human Anti-MCAM Recombinant Antibody (clone H10L2) | ELISA | Humanized IgG1 |
| HPAB-0495LY | Human Anti-MCAM Recombinant Antibody (clone H14L0) | ELISA | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0013-CN-F(E) | Human Anti-MCAM Recombinant Antibody (clone ScFv7); Fab Fragment | IP, FC | Human Fab |
| HPAB-0014-CN-F(E) | Human Anti-MCAM Recombinant Antibody (clone ScFv9); Fab Fragment | IP, FC | Human Fab |
| HPAB-0493LY-F(E) | Human Anti-MCAM Recombinant Antibody (clone H5L0); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0494LY-F(E) | Human Anti-MCAM Recombinant Antibody (clone H10L2); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0495LY-F(E) | Human Anti-MCAM Recombinant Antibody (clone H14L0); Fab Fragment | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0493LY-S(P) | Human Anti-MCAM Recombinant Antibody (clone H5L0); scfv Fragment | ELISA | Humanized scfv |
| HPAB-0494LY-S(P) | Human Anti-MCAM Recombinant Antibody (clone H10L2); scfv Fragment | ELISA | Humanized scfv |
| HPAB-0495LY-S(P) | Human Anti-MCAM Recombinant Antibody (clone H14L0); scfv Fragment | ELISA | Humanized scfv |
| HPAB-0496LY-S(P) | Human Anti-MCAM Recombinant Antibody (clone H11L3); scfv Fragment | ELISA | Humanized scfv |
| HPAB-0497LY-S(P) | Human Anti-MCAM Recombinant Antibody (clone H11L4); scfv Fragment | ELISA | Humanized scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY42 | Mouse Anti-MCAM (clone AA98) scFv-Fc Chimera | ELISA, FC, Inhib, IHC-Fr, WB, IP | Human IgG1, scFv-Fc |
| VS-0125-FY43 | Mouse Anti-MCAM (clone B6-11) scFv-Fc Chimera | WB, ELISA, IF | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC149 | Recombinant Anti-MCAM Vesicular Antibody, EV Displayed (VS-0425-YC149) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4291 | Anti-MCAM Immunohistochemistry Kit | IHC | |
| VS-0525-XY4292 | Anti-Mouse MCAM Immunohistochemistry Kit | IHC | |
| VS-0525-XY4293 | Anti-Rat MCAM Immunohistochemistry Kit | IHC |
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