Human Anti-MMP2 Recombinant Antibody (clone 3G11) (CAT#: FAMAB-1212CQ)
This product is a recombinant human antibody that recognizes MMP2. The antibody was purified by affinity chromatography. It can be used in ELISA.
Specific Inquiry
IHC
Figure 1 Immunohistochemical staining of mAb 3G11 in human colon carcinoma section.
A: Colon carcinoma (100×, the bar represents 400 μm in length.); B: the same case of A (400×, the bar represents 100 μm in length.); C (100×) and D (400×): another case of typical colon adenocarcinoma.
Li, L., Huang, Y. H., Li, Y., Wang, F. Q., Shang, B. Y., & Zhen, Y. S. (2005). Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma. World Journal of Gastroenterology: WJG, 11(29), 4478.
WB
Figure 2 Immunological property of mAb 3G11 by Western blot analysis.
Lane 1: human colon cancer HT-29 cell lysate; Lane 2: human fibrosarcoma HT-1080 cell lysate; Lane 3: human breast cancer tissue lysate.
Li, L., Huang, Y. H., Li, Y., Wang, F. Q., Shang, B. Y., & Zhen, Y. S. (2005). Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma. World Journal of Gastroenterology: WJG, 11(29), 4478.
Figure 3 Gelatin-zymography assay of HT-29 cells after treatment with mAb 3G11 at different concentrations.
Li, L., Huang, Y. H., Li, Y., Wang, F. Q., Shang, B. Y., & Zhen, Y. S. (2005). Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma. World Journal of Gastroenterology: WJG, 11(29), 4478.
ELISA
Figure 4 Immunoreactivity of 3G11(A) and 3G11-LDM (B) with type IV collagenase and various cancer cells in ELISA.
Li, L., Huang, Y. H., Li, Y., Wang, F. Q., Shang, B. Y., & Zhen, Y. S. (2005). Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma. World Journal of Gastroenterology: WJG, 11(29), 4478.
Specifications
- Immunogen
- Recombinant human type IV collagenase
- Host Species
- Human
- Type
- Human IgG1
- Species Reactivity
- Human
- Clone
- 3G11
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Matrix Metallopeptidase 2; Matrix Metalloproteinase-2; EC 3.4.24.24; CLG4A; MMP-2; TBE-1; Matrix Metalloproteinase 2 (Gelatinase A, 72kDa Gelatinase, 72kDa Type IV Collagenase); Matrix Metallopeptidase 2 (Gelatinase A, 72kDa Gelatinase, 72kDa Type IV Collagenase); Matrix Metalloproteinase-II; 72 KDa Type IV Collagenase
- Gene ID
- 4313
- UniProt ID
- P08253
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MMP2"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-666-F(E) | Recombinant Anti-human MMP2 Antibody Fab Fragment | FC, Neut, Funcs | Fab |
| MHH-666-F(E) | Recombinant Human Anti-human MMP2 Antibody Fab Fragment | WB, FC, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-666-S(P) | Recombinant Anti-human MMP2 Antibody scFv Fragment | FC, WB, FuncS | scFv |
| MHH-666-S(P) | Recombinant Human Anti-human MMP2 Antibody scFv Fragment | IF, Neut, FuncS | scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-666 | Recombinant Human Anti-human MMP2 Antibody | IF, FACS, FuncS | IgG |
| MRO-1012-CN | Recombinant Rabbit Anti-MMP2 Monoclonal Antibody (CBACN-378) | IHC | Rabbit IgG |
| MOB-0107F | Mouse Anti-MMP2 Recombinant Antibody (clone 1H1) | IHC-P, IF | Mouse IgG |
| ZG-0286C | Mouse Anti-MMP2 Recombinant Antibody (ZG-0286C) | WB | Mouse IgG |
| ZG-0729F | Mouse Anti-MMP2 Recombinant Antibody (clone 4D3) | ELISA, WB, IHC | Mouse IgG1 |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0566CL | Mouse Anti-MMP2 Recombinant Antibody (TAB-0566CL) | Inhib | Mouse IgG |
| TAB-0566CL-S(P) | Mouse Anti-MMP2 Recombinant Antibody; scFv Fragment (TAB-0566CL-S(P)) | Inhib | Mouse scFv |
| TAB-0566CL-F(E) | Mouse Anti-MMP2 Recombinant Antibody; Fab Fragment (TAB-0566CL-F(E)) | Inhib | Mouse Fab |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0365MZ | Chicken Anti-MMP2 Polyclonal IgY | WB | Chicken antibody |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1747CQ | Recombinant Mouse Anti-MMP2 Antibody (CA719E3C) | Inhib, IHC, WB, ICC | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2253 | Hi-Affi™ Recombinant Rabbit Anti-MMP2 Monoclonal Antibody (DS2253AB) | WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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