Mouse Anti-MR1 Recombinant Antibody (VS3-FY2807) (CAT#: VS3-FY2807)
The anti-MR1 antibody is a mouse recombinant monoclonal antibody, which has been intricately crafted to target the human MR1 protein. The calculated molecular weight of the protein is about 39.4 kDa. The antibody can be utilized for detection of MR1 by Immunohistochemistry (1/50-1/200) and Immunocytochemistry (1/50-1/200), Flow cytometry (1/50-1/200) and ELISA (1/1000-1/10000).
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48304/1582_D1_3_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48304/1582_D1_3_selected.jpg
Figure 2 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000153029-MR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000153029-MR1
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human MR1
- Species Reactivity
- Human
- Applications
- Immunohistochemistry, Immunocytochemistry, Flow cytometry, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 39.4 kDa.
- Related Disease
- Immune Deficiency Disease and Hemochromatosis, Type 1
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry: 1/50-1/200
Immunocytochemistry: 1/50-1/200
Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- Major Histocompatibility Complex, Class I-Related; Major Histocompatibility Complex, Class I-Like Sequence; Major Histocompatibility Complex Class I-Related Gene Protein; Class I Histocompatibility Antigen-Like Protein; MHC Class-I Related-Gene Protein; MHC Class I-Related Gene Protein; MHC Class I-Like Antigen MR-1; HLALS
- Gene ID
- 3140
- UniProt ID
- Q95460
- Sequence Similarities
- Belongs to the MHC class I family.
- Cellular Localization
- Cell membrane
Single-pass type I membrane protein
- Post Translation Modifications
- N-glycosylated. (Q95460-HMR1_HUMAN)
Glycosylation at Asn107 (NX_Q95460 [NX_Q95460-1])
Ubiquitination at Lys195 (NX_Q95460 [NX_Q95460-1])
Modification sites at PhosphoSitePlus (Q95460)
Glycosylation from GlyGen (Q95460) 1 site
- Protein Refseq
- XP_047274855.1; XP_054192199.1; XP_054192200.1; NP_001181928.1
- Function
- Acts as an immune sensor of cancer cell metabolome (PubMed:31959982).
May present a tumor-specific or -associated metabolite essential for cancer cell survival to a pan-cancer TCR consisting of TRAV38.2-DV8*TRAJ31 alpha chain paired with a TRBV25.1*TRBJ2.3 beta chain on a non-MAIT CD8-positive T cell clone (MC.7.G5), triggering T cell-mediated killing of a wide range of cancer cell types.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MR1"
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IgG Antibody Products
Blocking Antibody Products
MR1 Tetramer Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1255CT | Recombinant Mouse anti-Human MR1 Monoclonal antibody (EML391) | WB | |
| VS7-0425-WR412 | Mouse Anti-MR1 Recombinant Antibody (clone 6A5B2) | IHC, ICC, FC | Mouse IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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