Mouse Anti-MYCN Recombinant Antibody (clone 2A4E9) (CAT#: VS7-0425-WR449)
This product is a mouse IgG1 antibody that binds to human MYCN. The antibody 2A4E9 recognizes specific amino acid domain of human MYCN (AA: 337-464). It can be used for IHC and FC assays.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line RH-30
(Immunofluorescent staining of human cell line RH-30 shows localization to nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57420/1610_C12_1_selected.jpg
(Immunofluorescent staining of human cell line RH-30 shows localization to nucleoli.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57420/1610_C12_1_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (AF22, BEWO, HMC-1, NTERA-2, RH-30, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134323-MYCN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134323-MYCN
Specifications
- Immunogen
- Recombinant human MYCN (AA: 337-464) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human MYCN
- Species Reactivity
- Human
- Clone
- 2A4E9
- Molecule Class
- Helix-Loop-Helix Transcription Factor
- Applications
- IHC, FC
- Conjugate
- Unconjugated
- Related Disease
- Feingold syndrome 1 (FGLDS1); Megalencephaly-polydactyly syndrome (MPAPA)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry-Paraffin: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- MYCN; ODED; Pp65/67; N-Myc Proto-Oncogene Protein; V-Myc Avian Myelocytomatosis Viral Oncogene Neuroblastoma Derived Homolog; Class E Basic Helix-Loop-Helix Protein 37; Oncogene NMYC; NMYC; Neuroblastoma-Derived V-Myc Avian Myelocytomatosis Viral Related
- Gene ID
- 4613
- UniProt ID
- P04198
- Long Name
- MYCN Proto-Oncogene, BHLH Transcription Factor
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Phosphoprotein
- Protein Refseq
- NP_001280157.1
- Function
- Activator; DNA-binding
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IgG Antibody Products
MHC Tetramer Products for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3997z | Mouse Anti-MYCN Recombinant Antibody (clone 18H10) | WB, IP, IF | Mouse IgG2a |
| MOB-2256CT | Recombinant Mouse anti-Human MYCN Monoclonal antibody (3H4) | WB | |
| VS3-FY2814 | Mouse Anti-MYCN Recombinant Antibody (VS3-FY2814) | IHC, FC, ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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