Mouse Anti-NHP SAMHD1 Recombinant Antibody (clone OTI3F5) (CAT#: VS-1024-XY461)
Specifically designed to target SAMHD1, this advanced monoclonal antibody demonstrates outstanding reactivity with human, mouse, non-human primate, and rat samples. Utilizing a full-length human recombinant protein of SAMHD1 as the immunogen, it ensures exceptional specificity and binding affinity. Its broad applicability spans Western blotting, immunohistochemistry, immunofluorescence, and flow cytometry, making it an indispensable tool for researchers investigating the critical roles of SAMHD1 in cellular function and immune response. This antibody's reliability and versatility position it as a key resource for uncovering the complexities of SAMHD1 in various biological contexts.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/if_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/if_selected.jpg
Figure 2 Lymph node
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/123370_A_7_8.jpg
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/123370_A_7_8.jpg
Figure 3 Small intestine
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/123370_A_4_2.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/123370_A_4_2.jpg
Figure 4 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/123370_A_9_3.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/123370_A_9_3.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/123370_A_9_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/123370_A_9_5.jpg
Figure 6 Testis
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Peritubular cells Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/123370_A_6_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Peritubular cells Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47072/123370_A_6_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (ASC diff, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101347-SAMHD1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101347-SAMHD1
Specifications
- Immunogen
- Full length human recombinant protein of SAMHD1
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- SAMHD1
- Species Reactivity
- Human, Mouse, Non-human primate, Rat
- Clone
- OTI3F5
- Applications
- WB, IHC, IF, FC
Product Property
- Purification
- Protein A purified
- Purity
- >95%, determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS, pH 7.4, with 1% BSA, 50% glycerol
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- WB: 1:200-1:500, IHC: 1:200, IF: 1:100, FC: 1:100
Target
Recommended Products
Recommended Dilution Buffer
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3169 | Hi-Affi™ Recombinant Rabbit Anti-SAMHD1 Monoclonal Antibody (DS3169AB) | WB, IHC-P, ICC/IF, FC | IgG |
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For Research Use Only. Not For Clinical Use.
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