Rabbit Anti-NKX3-1 Recombinant Antibody (VS13-YC813)

CAT#: VS13-YC813

The Rabbit Anti-NKX3-1 Recombinant Antibody is specific for human NKX3-1. NKX3-1 is a homeobox transcription factor, regulating prostate tissue epithelial growth, with aberrant expression tied to tumor progression. The anti-NKX3-1 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100).

Gene Expression
Figure 1 High expression in prostate Figure 2 Low expression in skin 1 Figure 3 Testis Figure 4 Prostate Figure 5 RNA cell line category: Cell line enhanced (GAMG, SiHa, U-138 MG, U-251 MG)

Specifications

  • Immunogen
  • Recombinant human Nkx3.1.
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human NKX3-1
  • Species Reactivity
  • Human
  • Applications
  • WB, IHC-P
  • Conjugate
  • NONE
  • Related Disease
  • Rete Testis Neoplasm; Rete Testis Adenocarcinoma

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Affinity Chromatography purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.
  • Preservative
  • 0.02% Sodium azide
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Shipping with ice pack.

Applications

  • Application Notes
  • Western blot (WB): 1/500-1/1000
    Immunohistochemistry (IHC): 1/50-1/100

Target

  • Alternative Names
  • NK3 Homeobox 1; Homeobox Protein NK-3 Homolog A; NKX3.1; NKX3A; NK3 Transcription Factor Related, Locus 1 (Drosophila); NK3 Transcription Factor Related, Locus 1; NK Homeobox (Drosophila), Family 3, A;
  • Long Name
  • NK3 Homeobox 1
  • Cellular Localization
  • Nucleus
  • Function
  • Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor.
    Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate.
    Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Secondary Antibody

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