Rabbit Anti-NLRP3 Polyclonal Antibody (VS13-YC816)
CAT#: VS13-YC816
The Rabbit Anti-NLRP3 Polyclonal Antibody is specific for human, mouse and rat NLRP3. NLRP3 encodes a pyrin-like protein part of the NALP3 inflammasome, involved in innate immunity and inflammatory responses. Mutations relate to conditions like FCAS and MWS, with splicing variants diversifying its function. The anti-NLRP3 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100), Immunofluorescence (1/50-1/200).
Gene Expression
Normal Tissue
Figure 1 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows moderate cytoplasmic positivity in germinal and non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12878/29164_A_6_8_selected.jpg
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Specifications
- Immunogen
- Recombinant human NALP3.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat NLRP3
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC, IF
- Conjugate
- NONE
- Related Disease
- Familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), Chronic infantile neurological cutaneous and articular (CINCA) syndrome, and Neonatal-onset multisystem inflammatory disease (NOMID)
Product Property
- Clonality
- Polyclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 10 mM PBS (pH 7.4) containing 150 mM NaCl, 50% Glycerol and 0.05% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunofluorescence (IF): 1/50-1/200
Target
- Alternative Names
- NLR Family Pyrin Domain Containing 3; Cryopyrin; Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And Pyrin Domain Containing 3; Cold-Induced Autoinflammatory Syndrome 1 Protein; PYRIN-Containing APAF1-Like Protein 1; Caterpiller Protein 1.1; C1orf7; CLR1.1; PYPAF1; CIAS1; NALP3; NACHT Domain-, Leucine-Rich Repeat-, And PYD-Containing Protein 3; NACHT, LRR And PYD Domains-Containing Protein 3;
- Gene ID
- 114548
- UniProt ID
- Q96P20
- Long Name
- NLR Family Pyrin Domain Containing 3
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "NLRP3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2811z | Mouse Anti-NLRP3 Recombinant Antibody (MOB-2811z) | WB, IHC, IHC-Fr, IHC-P, IP | Mouse IgG1 |
| MRO-1097-CN | Recombinant Rabbit Anti-NLRP3 Monoclonal Antibody (CBACN-403) | WB, IF, IHC, IP, FC | Rabbit IgG |
| MRO-2076-CN | Rabbit Anti-NLRP3 Polyclonal Antibody (MRO-2076-CN) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-WK1107 | Rabbit Anti-NLRP3 Recombinant Antibody (VS3-WK1107) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
| VS3-FY1046 | Recombinant Rabbit Anti-NLRP3 Antibody (clone R07-9E9) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2811z-F(E) | Recombinant Anti-Human NLRP3 Antibody Fab Fragment | WB, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2811z-S(P) | Recombinant Anti-Human NLRP3 Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2453 | Hi-Affi™ Recombinant Rabbit Anti-NLRP3 Monoclonal Antibody (DS2453AB) | FC, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1499 | Anti-NLRP3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4870 | Anti-Mouse NLRP3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4869 | Anti-Human NLRP3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC817 | CytoStream™ Rabbit Anti-NLRP3 Recombinant Antibody (VS13-YC817) | WB, IHC-P, ICC, IF, FC | Rabbit IgG |
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