CytoStream™ Rabbit Anti-PDE4B Recombinant Antibody (VS13-YC883) (CAT#: VS13-YC883)
The CytoStream™ Rabbit Anti-PDE4B Recombinant Antibody is specific for human and mouse PDE4B. PDE4B encodes a cAMP-specific phosphodiesterase impacting cellular signaling, linked to psychiatric disorders like schizophrenia, showing spliced transcript variants. The anti-PDE4B antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line AF22
(Immunofluorescent staining of human cell line AF22 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/1786_F1_2_selected.jpg
(Immunofluorescent staining of human cell line AF22 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/1786_F1_2_selected.jpg
Figure 2 IHC staining of human epididymis
(Immunohistochemical staining of human epididymis shows strong cytoplasmic positivity with granular pattern in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/ihc_selected.jpg
(Immunohistochemical staining of human epididymis shows strong cytoplasmic positivity with granular pattern in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/ihc_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_B_7_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_B_7_5.jpg
Figure 4 Lung
(Alveolar cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Macrophages Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_A_2_4.jpg
(Alveolar cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Macrophages Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_A_2_4.jpg
Figure 5 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_A_7_3.jpg
Figure 6 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_A_7_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_A_7_4.jpg
Figure 7 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_A_7_5.jpg
Figure 8 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_A_4_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3005/9074_A_4_6.jpg
Figure 9 RNA cell line category: Cell line enhanced (AN3-CA, HUVEC TERT2, NTERA-2, SK-MEL-30, TIME, U-266/84)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000184588-PDE4B
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000184588-PDE4B
Specifications
- Immunogen
- Recombinant human PDE4B.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse PDE4B
- Species Reactivity
- Human, Mouse
- Applications
- WB, FC
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 10 mM PBS (pH 7.4) containing 150 mM NaCl, 50% Glycerol and 0.05% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- Phosphodiesterase 4B; Phosphodiesterase 4B, CAMP-Specific (Phosphodiesterase E4 Dunce Homolog, Drosophila); CAMP-Specific 3, 5-Cyclic Phosphodiesterase 4B; DPDE4; Phosphodiesterase 4B, CAMP-Specific (Dunce (Drosophila)-Homolog Phosphodiesterase E4); Phosphodiesterase E4 Dunce Homolog (Drosophila); Phosphodiesterase 4B, CAMP-Specific;
- Gene ID
- 5142
- UniProt ID
- Q07343
- Long Name
- Phosphodiesterase 4B
- Function
- Signal transduction
Recommended Products
Secondary Antibody
Isotype Control
Related Resources
cAMP Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "PDE4B"
Select a product category from the dropdown menu below to view related products.
Please select product type
Rabbit Monoclonal Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2631 | Hi-Affi™ Recombinant Rabbit Anti-PDE4B Monoclonal Antibody (DS2631AB) | WB, FC | IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS13-YC883. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
-1.png)
Application: WB, ELISA
Application: WB, ELISA, FuncS, IB, FC, SPR, Apop
Application: FC, IHC-Fr, IP, ELISA, Block
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FC, Inhib, FuncS
Application: FC, IA, IF, IP, IHC, FuncS
Application: ELISA, Cyt, PP, Inhib
Application: ELISA, Neut
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
