Mouse Anti-PGF Recombinant Antibody (clone 5D11D4) (CAT#: HPAB-0615YY)
This product is a recombinant Mouse antibody that recognizes (both natural and recombinant) Mouse PGF.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Inhib
Figure 1 Inhibition of PlGF Leads to Regression of Medulloblastoma.
Murine-specific anti-PlGF Ab 5D11D4 (amPlGF) shows significantly tumor size inhibition effect in Smo/Smo spontaneous model of medulloblastoma. Measured in cross-section.
Snuderl, M., Batista, A., Kirkpatrick, N. D., de Almodovar, C. R., Riedemann, L., Walsh, E. C., ... & Knevels, E. (2013). Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell, 152(5), 1065-1076.
Inhib
Figure 2 Inhibition of stromal PlGF in D283-MED or D341-MED tumors by anti-mouse PlGF (amPlGF) 5D11D4 led to delayed growth and stabilization of the tumor.
In the D283-MED model, treatment with amPlGF 5D11D4 from day 1 after implantation (D283 amPlGFP, prevention trial) led to a growth delay similar to shPlGF inhibition.
Snuderl, M., Batista, A., Kirkpatrick, N. D., de Almodovar, C. R., Riedemann, L., Walsh, E. C., ... & Knevels, E. (2013). Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell, 152(5), 1065-1076.
Specifications
- Immunogen
- hPlGF1
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Mouse
- Species Reactivity
- Mouse
- Clone
- 5D11D4
- Applications
- Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The PGF antibody has been reported in applications of Inhibition.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1735z | Mouse Anti-PGF Recombinant Antibody (clone 28A4) | WB, ICC, IF, IHC | Mouse IgG1 |
| MOB-1275CT | Recombinant Mouse anti-Human PGF Monoclonal antibody (48304.222) | ELISA, WB | |
| HPAB-0401-CN | Mouse Anti-PGF Recombinant Antibody (clone C9.V2) | WB, ELISA, Block | Mouse IgG2a, κ |
| MRO-2126-CN | Rabbit Anti-PGF Polyclonal Antibody (MRO-2126-CN) | IHC, FC | Rabbit IgG |
| ZG-0510U | Rabbit Anti-PGF Recombinant Antibody (clone 1B6) | ELISA, IHC | Rabbit IgG |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# HPAB-0615YY, RRID: AB_3111403)
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