Mouse Anti-PGF Recombinant Antibody (clone 5D11D4)
CAT#: HPAB-0615YY
This product is a recombinant Mouse antibody that recognizes (both natural and recombinant) Mouse PGF.
Published Data
Gene Expression
Inhib
Figure 1 Inhibition of PlGF Leads to Regression of Medulloblastoma.
Murine-specific anti-PlGF Ab 5D11D4 (amPlGF) shows significantly tumor size inhibition effect in Smo/Smo spontaneous model of medulloblastoma. Measured in cross-section.
Snuderl, M., Batista, A., Kirkpatrick, N. D., de Almodovar, C. R., Riedemann, L., Walsh, E. C., ... & Knevels, E. (2013). Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell, 152(5), 1065-1076.
Inhib
Figure 2 Inhibition of stromal PlGF in D283-MED or D341-MED tumors by anti-mouse PlGF (amPlGF) 5D11D4 led to delayed growth and stabilization of the tumor.
In the D283-MED model, treatment with amPlGF 5D11D4 from day 1 after implantation (D283 amPlGFP, prevention trial) led to a growth delay similar to shPlGF inhibition.
Snuderl, M., Batista, A., Kirkpatrick, N. D., de Almodovar, C. R., Riedemann, L., Walsh, E. C., ... & Knevels, E. (2013). Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell, 152(5), 1065-1076.
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Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/41624/if_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (BEWO, HUVEC TERT2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000119630-PGF
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Specifications
- Immunogen
- hPlGF1
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Mouse
- Species Reactivity
- Mouse
- Clone
- 5D11D4
- Applications
- Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The PGF antibody has been reported in applications of Inhibition.
Target
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# HPAB-0615YY, RRID: AB_3111403)
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 5D11D4"
- CAT
- Product Name
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Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1735z | Mouse Anti-PGF Recombinant Antibody (clone 28A4) | WB, ICC, IF, IHC | Mouse IgG1 |
| MRO-1247-CN | Recombinant Mouse Anti-PGF Monoclonal Antibody (3G3) | WB, IHC, IF | Mouse IgG1 |
| MRO-1248-CN | Recombinant Mouse Anti-PGF Monoclonal Antibody (3G2) | WB, IHC, IF | Mouse IgG1 |
| MRO-2126-CN | Rabbit Anti-PGF Polyclonal Antibody (MRO-2126-CN) | IHC, FC | Rabbit IgG |
| ZG-0510U | Rabbit Anti-PGF Recombinant Antibody (clone 1B6) | ELISA, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-022 | Recombinant Anti-Mouse Pgf VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1041CL | Mouse Anti-PGF Recombinant Antibody (TAB-1041CL) | ELISA, Inhib, FuncS | Mouse IgG |
| TAB-1041CL-S(P) | Mouse Anti-PGF Recombinant Antibody; scFv Fragment (TAB-1041CL-S(P)) | ELISA | Mouse scFv |
| TAB-1041CL-F(E) | Mouse Anti-PGF Recombinant Antibody; Fab Fragment (TAB-1041CL-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1042CL | Human Anti-PGF Recombinant Antibody (TAB-1042CL) | ELISA, Inhib | Human IgG4, κ |
| TAB-1042CL-S(P) | Human Anti-PGF Recombinant Antibody; scFv Fragment (TAB-1042CL-S(P)) | ELISA | Human scFv |
| TAB-1042CL-F(E) | Human Anti-PGF Recombinant Antibody; Fab Fragment (TAB-1042CL-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1857CQ | Recombinant Rat Anti-Pgf Antibody (9G33) | WB, Neut | IgG2 |
| NEUT-1858CQ | Recombinant Rat Anti-Pgf Antibody (62526.111) | ELISA, Neut, WB | IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1859CQ | Recombinant Rat Anti-Pgf Antibody (CBL304) | BL, WB | IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2680 | Hi-Affi™ Recombinant Rabbit Anti-PGF Monoclonal Antibody (DS2680AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0401-CN-S(P) | Mouse Anti-PGF Recombinant Antibody (clone C9.V2); scFv Fragment | WB, ELISA, Block | Mouse scFv |
| HPAB-0615YY-S(P) | Mouse Anti-PGF Recombinant Antibody (clone 5D11D4); scFv Fragment | Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0401-CN-F(E) | Mouse Anti-PGF Recombinant Antibody (clone C9.V2); Fab Fragment | WB, ELISA, Block | Mouse Fab |
| HPAB-0615YY-F(E) | Mouse Anti-PGF Recombinant Antibody (clone 5D11D4); Fab Fragment | Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1627 | Anti-PGF Immunohistochemistry Kit | IHC | |
| VS-0525-XY5345 | Anti-Mouse PGF Immunohistochemistry Kit | IHC | |
| VS-0525-XY5344 | Anti-Human PGF Immunohistochemistry Kit | IHC |
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