AibGenesis™ Rabbit Anti-PSMA1 Recombinant Antibody (AibG-Rb-PS681)
CAT#: VS-0426-FY681
Developed on an AI-powered antibody discovery platform, this antibody targets the proteasome for neurodevelopmental research, ensuring versatility in WB, IHC, and FC.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37646/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human testis
Immunohistochemical staining of human testis shows distinct cytoplasmic and nuclear positivity in cells in seminiferus ducts and Leydig cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37646/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Glial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37646/78642_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37646/78642_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37646/78642_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37646/78642_A_7_5.jpg
Normal Tissue
Figure 7 Testis
Elongated or late spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37646/78642_A_5_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37646/78642_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000129084-PSMA1/subcellular
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Specifications
- Immunogen
- Human
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human PSMA1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- AibG-Rb-PS681
- Applications
- Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Flow Cytometry, Immunoprecipitation
- Conjugate
- Unconjugated, Biotin and FITC are available.
- Related Disease
- Neurodevelopmental Disorders
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- PBS, 0.05% Protective protein, 50% Glycerol
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (1:1000-1:2000), Immunohistochemistry (1:100-1:200), Immunocytochemistry/Immunofluorescence (1:50-1:200), Immunocytochemistry (1:50-1:200), Flow Cytometry (1:20-1:100), Immunoprecipitation (1:20-1:50)
Target
- Alternative Names
- NU; HC2; PROS30; psmA1; PSC2; Proteasome 20S C2; PSMA1
- UniProt ID
- P25786
- Long Name
- Proteasome 20S Subunit Alpha 1
- Sequence Similarities
- Belongs to the peptidase T1A family.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Glycosylation at Ser110 (NX_P25786 [NX_P25786-1])
Ubiquitination at Lys30, Lys50, Lys115, Lys189, Lys208, Lys243, and Lys256 (NX_P25786 [NX_P25786-1])
Modification sites at PhosphoSitePlus (P25786)
Glycosylation from GlyGen (P25786) 2 sites, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001137409.1; NP_002777.1; NP_683877.1
- Function
- The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "PSMA1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3070z | Mouse Anti-PSMA1 Recombinant Antibody (clone 36H6) | WB, ELISA, ICC, IF, IHC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1707CT | Recombinant Mouse anti-Human PSMA1 Monoclonal antibody (NDQ30) | ICC, IF, IP, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0443MZ | Chicken Anti-PSMA1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2887 | Hi-Affi™ Recombinant Rabbit Anti-PSMA1 Monoclonal Antibody (DS2887AB) | WB, IHC, ICC, IP, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4241 | PE-A*02:03/Human PSMA1 (NLNELVKHGL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4242 | PE-A*02:02/Human PSMA1 (NLNELVKHGL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4243 | PE-A*02:01/Human PSMA1 (HMSEFMECNL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4244 | PE-A*02:02/Human PSMA1 (HMSEFMECNL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4245 | PE-A*02:03/Human PSMA1 (HMSEFMECNL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1277-CN | Recombinant Rabbit Anti-PSMA1 Monoclonal Antibody (JB89-30) | WB, IHC, FC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1288-CN | Recombinant Rabbit Anti-PSMA1 Monoclonal Antibody (JU66-24) | WB, IF, IHC, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY218 | AbPlus™ Anti-PSMA1 Magnetic Beads (JB89-30) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1398 | AbPlus™ Anti-PSMA1 Magnetic Beads (VS-0724-YC1398) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1775 | Anti-PSMA1 Immunohistochemistry Kit | IHC |
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