CytoStream™ Rabbit Anti-PTPRC Recombinant Antibody (VS13-YC960)

CAT#: VS13-YC960

The CytoStream™ Rabbit Anti-PTPRC Recombinant Antibody is specific for human PTPRC. PTPRC encodes a receptor-type phosphatase crucial for antigen receptor signaling in lymphocyte activation. The anti-PTPRC antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).

Gene Expression
Figure 1 IF staining of human cell line A-431 Figure 2 Appendix Figure 3 Lymph node Figure 4 RNA cell line category: Cell line enhanced (Daudi, HEL, HL-60, JURKAT, MOLT-4, THP-1, U-266/70, U-266/84, U-698, U-937)

Specifications

  • Immunogen
  • Recombinant human CD45, aa 1210-1306.
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human PTPRC
  • Species Reactivity
  • Human
  • Applications
  • WB, IHC-P, FC
  • Conjugate
  • NONE

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein A purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
  • Preservative
  • 0.05% Sodium azide
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Shipping with ice pack.

Applications

  • Application Notes
  • Western blot (WB): 1/500-1/1000
    Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
    Flow cytometry (FC): 1/50-1/100

Target

  • Alternative Names
  • CD45
  • Long Name
  • Protein Tyrosine Phosphatase Receptor Type C
  • Sequence Similarities
  • Belongs to the protein-tyrosine phosphatase family. Receptor class 1/6 subfamily.
  • Cellular Localization
  • Cell junction; Cell membrane
  • Function
  • Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
    (Microbial infection) Acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation.
REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS
Inquiry
Navs

Customer Review

Submit a review or a question

There are currently no Customer reviews or questions for VS13-YC960. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Article title:
DOI/PubMed URL:
Email:
Name:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Secondary Antibody

Isotype Control

See other products for "PTPRC"

Select a product category from the dropdown menu below to view related products.

CAT Product Name Application Type
BRD-0466MZ Chicken Anti-PTPRC Polyclonal IgY WB Chicken antibody
CAT Product Name Application Type
NEUT-1895CQ Recombinant Mouse Anti-PTPRC Antibody (HI30) WB, IP, IHC-Fr, FuncS, ICC, FC, IHC-P, BL IgG1
NEUT-1896CQ Recombinant Mouse Anti-Ptprc Antibody (104-2) FC, IP, BL, IHC-Fr, ICC, IF IgG2a, κ
NEUT-1897CQ Recombinant Rat Anti-Ptprc Antibody (MAB0822) BL, FC, IP, WB IgG2
NEUT-1898CQ Recombinant Rat Anti-Ptprc Antibody (RA3-6B2) FC, IHC-Fr, IHC-P, IP, WB, BL IgG2a, κ
CAT Product Name Application Type
VS-0424-XY220 AbPlus™ Anti-PTPRC Magnetic Beads (YTH54.12) IP, Protein Purification
VS-0724-YC1181 AbPlus™ Anti-PTPRC Magnetic Beads (VS-0724-YC1181) IP, Protein Purification
CAT Product Name Application Type
VS-1024-XY98 Mouse Anti-NHP PTPRC Recombinant Antibody (clone MEM55) IHC, FC Mouse IgG1
CAT Product Name Application Type
VS-0425-FY86 Human Anti-PTPRC (clone VHE-N73D/humV1) scFv-Fc Chimera IF, FC Human IgG1, scFv-Fc
CAT Product Name Application Type
VS-0425-YC529 Recombinant Anti-PTPRC Vesicular Antibody, EV Displayed (VS-0425-YC529) ELISA, FC, Neut, Cell-uptake
Specific Inquiry
Go to compare Add to compare

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Go to compare

Go to compare