CytoStream™ Rabbit Anti-PTPRC Recombinant Antibody (VS13-YC960)
CAT#: VS13-YC960
The CytoStream™ Rabbit Anti-PTPRC Recombinant Antibody is specific for human PTPRC. PTPRC encodes a receptor-type phosphatase crucial for antigen receptor signaling in lymphocyte activation. The anti-PTPRC antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).




Specifications
- Immunogen
- Recombinant human CD45, aa 1210-1306.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human PTPRC
- Species Reactivity
- Human
- Applications
- WB, IHC-P, FC
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- CD45
- Gene ID
- 5788
- UniProt ID
- P08575
- Long Name
- Protein Tyrosine Phosphatase Receptor Type C
- Sequence Similarities
- Belongs to the protein-tyrosine phosphatase family. Receptor class 1/6 subfamily.
- Cellular Localization
- Cell junction; Cell membrane
- Protein Refseq
- NP_002829.3; NP_563578.2
- Function
- Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
(Microbial infection) Acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation.
Customer Review
There are currently no Customer reviews or questions for VS13-YC960. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "PTPRC"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-240LC | Anti-Human PTPRC Recombinant Antibody (VHE/humV1) | Inhib | Humanized antibody |
TAB-241LC | Anti-Human PTPRC Recombinant Antibody (VHE/humV2) | Inhib | Humanized antibody |
TAB-240LC-F(E) | Anti-Human PTPRC Recombinant Antibody Fab Fragment (VHE/humV1) | ELISA, FC | Humanized antibody |
TAB-241LC-F(E) | Anti-Human PTPRC Recombinant Antibody Fab Fragment (VHE/humV2) | ELISA, FC | Humanized antibody |
TAB-242LC-F(E) | Anti-Human PTPRC Recombinant Antibody Fab Fragment (VHQ/humV1) | ELISA, FC | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-245LC-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (TAB-245LC-F(E)) | ELISA, FC | Human Fab |
TAB-246LC-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (TAB-246LC-F(E)) | ELISA, FC | Human Fab |
TAB-247LC-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (TAB-247LC-F(E)) | ELISA, FC | Human Fab |
TAB-248LC-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (TAB-248LC-F(E)) | ELISA, FC | Human Fab |
TAB-249LC-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (TAB-249LC-F(E)) | ELISA, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0466MZ | Chicken Anti-PTPRC Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1895CQ | Recombinant Mouse Anti-PTPRC Antibody (HI30) | WB, IP, IHC-Fr, FuncS, ICC, FC, IHC-P, BL | IgG1 |
NEUT-1896CQ | Recombinant Mouse Anti-Ptprc Antibody (104-2) | FC, IP, BL, IHC-Fr, ICC, IF | IgG2a, κ |
NEUT-1897CQ | Recombinant Rat Anti-Ptprc Antibody (MAB0822) | BL, FC, IP, WB | IgG2 |
NEUT-1898CQ | Recombinant Rat Anti-Ptprc Antibody (RA3-6B2) | FC, IHC-Fr, IHC-P, IP, WB, BL | IgG2a, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2933 | Hi-Affi™ Recombinant Rabbit Anti-PTPRC Monoclonal Antibody (DS2933AB) | IP, WB | IgG |
MOR-0089-FY | Rabbit Anti-PTPRC Recombinant Antibody (clone AFY0060) | ICC, IHC-P, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0365-CN-S(P) | Rabbit Anti-PTPRC Recombinant Antibody; scFv Fragment (HPAB-0365-CN-S(P)) | ELISA, FC | Rabbit scFv |
HPAB-0366-CN-S(P) | Human Anti-PTPRC Recombinant Antibody; scFv Fragment (HPAB-0366-CN-S(P)) | ELISA, FC | Human scFv |
HPAB-M0191-YC-S(P) | Human Anti-PTPRC Recombinant Antibody (clone M/YC-14); scFv Fragment | ELISA, WB | Human scFv |
HPAB-0536-FY-S(P) | Human Anti-PTPRC Recombinant Antibody; scFv Fragment (HPAB-0536-FY-S(P)) | Inhib, FuncS | Human scFv |
HPAB-0537-FY-S(P) | Mouse Anti-PTPRC Recombinant Antibody; scFv Fragment (HPAB-0537-FY-S(P)) | FC, Block | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-081LC | Recombinant Mouse Anti-Sheep CD45 Antibody | FC, IP | Mouse IgG |
HPAB-0536-FY | Human Anti-PTPRC Recombinant Antibody (HPAB-0536-FY) | Inhib, FuncS | Human IgG |
HPAB-0537-FY | Mouse Anti-PTPRC Recombinant Antibody (HPAB-0537-FY) | FC, Block, FuncS | Mouse IgG |
ZG-0116J | Mouse Anti-PTPRC Recombinant Antibody (ZG-0116J) | IHC-P, IF | Mouse IgG |
ZG-0117J | Mouse Anti-PTPRC Recombinant Antibody (ZG-0117J) | IHC-P, IF | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-023CN | Mouse Anti-PTPRC Recombinant Antibody (clone ZCH-6-3A4) | FC, IF | Mouse IgG1, κ |
NS-023CN-F(E) | Mouse Anti-PTPRC Recombinant Antibody (clone ZCH-6-3A4); Fab Fragment | FC, IF | Mouse Fab |
NS-023CN-S(P) | Mouse Anti-PTPRC Recombinant Antibody (clone ZCH-6-3A4); scFv Fragment | FC, IF | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0006-CN-F(E) | Mouse Anti-PTPRC Recombinant Antibody (clone LT40); Fab Fragment | FC | Mouse Fab |
HPAB-0258-FY-F(E) | Mouse Anti-PTPRC Recombinant Antibody; Fab Fragment (HPAB-0258-FY-F(E)) | ELISA | Mouse Fab |
HPAB-M0191-YC-F(E) | Human Anti-PTPRC Recombinant Antibody (clone M/YC-14); Fab Fragment | ELISA, WB | Human Fab |
HPAB-0536-FY-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (HPAB-0536-FY-F(E)) | Inhib, FuncS | Human Fab |
HPAB-0537-FY-F(E) | Mouse Anti-PTPRC Recombinant Antibody; Fab Fragment (HPAB-0537-FY-F(E)) | FC, Block | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0424-XY220 | AbPlus™ Anti-PTPRC Magnetic Beads (YTH54.12) | IP, Protein Purification | |
VS-0724-YC1181 | AbPlus™ Anti-PTPRC Magnetic Beads (VS-0724-YC1181) | IP, Protein Purification |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-1024-XY98 | Mouse Anti-NHP PTPRC Recombinant Antibody (clone MEM55) | IHC, FC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0225-XY185 | CytoStream™ Rat Anti-PTPRC Recombinant Antibody (clone 30-F11) | FC | Rat IgG2b, kappa |
VS-0225-XY186 | CytoStream™ Mouse Anti-PTPRC Recombinant Antibody (clone OX-33) | FC | Mouse IgG1, kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0425-FY86 | Human Anti-PTPRC (clone VHE-N73D/humV1) scFv-Fc Chimera | IF, FC | Human IgG1, scFv-Fc |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0425-YC529 | Recombinant Anti-PTPRC Vesicular Antibody, EV Displayed (VS-0425-YC529) | ELISA, FC, Neut, Cell-uptake |
Popular Products
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FuncS, Inhib, IP, ELISA
Application: ELISA, FC, IF, IHC, WB
Application: ELISA, IHC, IF, IP
Application: Inhib, FC, WB
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.