Camelid Anti-PYCARD Recombinant Single Domain Antibody (Clone VHHASC) (CAT#: PABS-0127)
This recombinant monoclonal antibody to human PYCARD is a Camelid monoclonal antibody that can be used for applications: ELISA, Block.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nucleoli & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49074/if_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nucleoli & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49074/if_selected.jpg
Figure 2 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong cytoplasmic and nuclear positivity in cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15948/36925_B_7_4_selected.jpg
(Immunohistochemical staining of human spleen shows strong cytoplasmic and nuclear positivity in cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15948/36925_B_7_4_selected.jpg
Figure 3 Colon
(Enterocytes
Staining: Low
Intensity: Weak
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49074/136467_A_8_3.jpg
(Enterocytes
Staining: Low
Intensity: Weak
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49074/136467_A_8_3.jpg
Figure 4 Lymph node
(Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49074/136467_A_8_8.jpg
(Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49074/136467_A_8_8.jpg
Figure 5 Spleen
(Cells in red pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49074/136467_B_7_4.jpg
(Cells in red pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49074/136467_B_7_4.jpg
Figure 6 RNA cell line category: Cell line enhanced (MCF7, NB-4, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000103490-PYCARD/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000103490-PYCARD/subcellular
Specifications
- Immunogen
- MBP-ASC
- Host Species
- Camelid
- Derivation
- Phage display library
- Type
- Camelid VHH
- Specificity
- Human PYCARD
- Species Reactivity
- Human
- Clone
- VHHASC
- Applications
- ELISA, Block, FuncS
- Related Disease
- Chronic recurrent multifocal osteomyelitis, Muckle-Wells syndrome
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2948 | Hi-Affi™ Recombinant Rabbit Anti-PYCARD Monoclonal Antibody (DS2948AB) | WB, IP, FC | IgG |
Customer Reviews and Q&As
Customer Review
Q&As
Ideal for Apoptosis Research
Using the Camelid Anti-PYCARD Antibody has significantly enhanced our apoptosis research. Its specificity to PYCARD allows us to track and analyze apoptotic bodies with increased precision, making it a valuable instrument in understanding cell death pathways.
Enhances Understanding of Immune Mechanisms
Utilizing this antibody has enriched our understanding of immune mechanisms via PYCARD signaling. It offers a clear window into how cells communicate signals of death and survival, further elucidating core immune functions.
Effective Research Tool
I recently used the Camelid Anti-PYCARD Recombinant Single Domain Antibody for my research on inflammation pathways, and found it to be a robust and reliable tool. The high sensitivity and specificity were especially beneficial for my experiments, enabling clear and reproducible results. It's a significant addition to my lab resources.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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