AbPlus™ Anti-RELA Magnetic Beads (CBACN-401)

CAT#: VS-0424-XY223

The AbPlus Anti-RELA Magnetic Beads (CBACN-401) is an innovative affinity resin which is bound with anti-RELA specific antibody (CBACN-401). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of RELA protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 IHC staining of human fallopian tube Figure 3 Testis Figure 4 Lymph node Figure 5 Cerebral cortex Figure 6 Colon Figure 7 Kidney Figure 8 RNA cell line category: Low cell line specificity

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magrose bead (> 50 μmol/mL gel)
  • Bead Ligand
  • Anti-RELA specific antibody (CBACN-401)
  • Target
  • RELA
  • Immunogen
  • Human RELA p65 (aa 500-551)
  • Target Species
  • Human, Mouse, Zebrafish
  • Antibody Clone
  • CBACN-401
  • Bead Capacity
  • 20-30 mg/mL binding antibody
  • Bead size
  • 10-37 μm
  • Stability
  • pH 2-14
  • Format
  • 20% Suspension
  • Buffer
  • PBS, pH 7.4, with 1% BSA
  • Preservative
  • 0.03% Proclin 300
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • RELA Proto-Oncogene, NF-KB Subunit; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 3; V-Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A; Nuclear Factor NF-Kappa-B P65 Subunit; NFKB3; V-Rel Reticuloendotheliosis Viral Oncogene Homolog A
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