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    Recombinant Anti-human RELA Intrabody [+36 GFP] (CAT#: IAB-B027(G))

    Recombinant anti-RELA intrabody in fusion with +36GFP works within cells against RELA, expressed in E. coli cells. This intrabody against p65 subunit can prevent nuclear factor nB (NF-nB) transcriptional activity in glioma cells andbindinhibit the expression of its target genes involved in the invasion and angiogenesis of human gliomas.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/63461/if_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human fallopian tube
    Figure 2 IHC staining of human fallopian tube
    (Immunohistochemical staining of human fallopian tube shows strong cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4264/18466_A_7_7_selected.jpg
    Figure 3 Testis
    Figure 3 Testis
    (Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4264/18466_A_5_6.jpg
    Figure 4 Lymph node
    Figure 4 Lymph node
    (Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4264/18466_A_8_8.jpg
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4264/18809_B_8_5.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4264/18466_A_7_3.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4264/18466_A_8_5.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000173039-RELA

    Specifications

    • Immunogen
    • human v-rel avian reticuloendotheliosis viral oncogene homolog A
    • Host Species
    • human
    • Type
    • scFv-(+36GFP)
    • Cell Penetrating Peptide
    • +36 GFP
      GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
    • Species Reactivity
    • human
    • Applications
    • Products can be used for: Immunofluorescence; Enzyme-linked Immunosorbent Assay; Functional studies

    Product Property

    • Purity
    • 90–95% (SDS-PAGE)
    • Storage
    • Store at -20°C. Open under aseptic conditions.

    Target

    • Alternative Names
    • RELA; v-rel avian reticuloendotheliosis viral oncogene homolog A; p65; NFKB3; transcription factor p65; NF-kappa-B p65delta3; nuclear factor NF-kappa-B p65 subunit; v-rel reticuloendotheliosis viral oncogene homolog A; nuclear factor of kappa light polype

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    Intrabody Products Chicken IgY Antibody Products Rabbit Monoclonal Antibody Products IgG Antibody Products Antibody Magnetic Beads Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research ScFv-Fc Chimera Products
    CAT Product Name Application Type
    IAB-B027(A) Recombinant Anti-human RELA Intrabody [(D-Arg)9] WB, CO-IP, FuncS scFv-(D-Arg)9
    IAB-B027(T) Recombinant Anti-human RELA Intrabody [Tat] FC, IF, FuncS scFv-Tat

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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