Mouse Anti-RELB Recombinant Antibody (RE582)
CAT#: VS-0326-YC582
The anti-RELB recombinant antibody (RE582) reacts with human RELB. RELB is a subunit of the non-canonical NF-κB pathway, primarily activated by receptors like LTbetaR and CD40. It forms heterodimers with p52 to regulate the development of secondary lymphoid organs and the maturation of dendritic cells. RELB signaling is essential for long-term immune homeostasis and the specification of lymphoid architecture. The anti-RELB antibody (RE582) has been tested in Enzyme-linked Immunosorbent Assay (ELISA), Immunocytochemistry (ICC), Immunohistochemistry (IHC) and Flow Cytometry (FC).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40506/if_selected.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40506/92847_A_9_8.jpg
Normal Tissue
Figure 3 Hippocampus
Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40506/92847_B_9_6.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40506/92847_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40506/92847_A_8_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40506/92847_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40506/92847_A_5_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, U-698)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104856-RELB
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human RELB
- Species Reactivity
- Human
- Clone
- RE582
- Applications
- ELISA, ICC, IHC, FC
- Conjugate
- The unconjugated, Biotin and FITC formats are available.
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- IHC (1/200-1/1000), ICC (1/200-1/1000), ELISA (1/5000-1/20000), FC (1/200-1/400)
Target
- Alternative Names
- RELB Proto-Oncogene, NF-KB Subunit; V-Rel Avian Reticuloendotheliosis Viral Oncogene Homolog B (Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 3); I-REL; V-Rel Reticuloendotheliosis Viral Oncogene Homolog B, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 3; Transcription Factor RelB; IMD53; REL-B; IREL;
- Gene ID
- 5971
- UniProt ID
- Q01201
- Long Name
- RELB Proto-Oncogene, NF-KB Subunit
- Post Translation Modifications
- Unmodified
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "RELB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3044 | Hi-Affi™ Recombinant Rabbit Anti-RELB Monoclonal Antibody (DS3044AB) | ICC, IF, IHC-P, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1328-CN | Recombinant Rabbit Anti-RELB Monoclonal Antibody (CBACN-480) | WB, IF, IHC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY1367 | Mouse Anti-RELB Recombinant Antibody (clone 2E4B1) | ICC, FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK841 | Mouse Anti-RELB Recombinant Antibody (VS3-WK841) | WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK842 | Rabbit Anti-RELB Recombinant Antibody (VS3-WK842) | WB, ICC, IF, IHC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY1266 | Recombinant Rabbit Anti-RELB Antibody (clone R07-9J3) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY445 | Rabbit Anti-NHP RELB Recombinant Antibody (VS-1024-XY445) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1906 | Anti-RELB Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6075 | Anti-Mouse RELB Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6074 | Anti-Human RELB Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0925-LX9 | Mouse Anti-RelB Monoclonal Antibody, Rhesus Monkey, Mouse Cross Reactivity | Cross Reactivity Study | Monoclonal Antibody |
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