AibGenesis™ Rabbit Anti-RPS6KA3 Recombinant Antibody (AibG-Rb-PS337)
CAT#: VS14-YC541
Developed through sophisticated AI architectures, the anti-RPS6KA3 antibody demonstrates robust immunoreactivity toward human and rodent RPS6KA3. RPS6KA3 (RSK2) is a member of the RSK family that facilitates growth factor-induced gene expression via the MAPK pathway. Mutations in this kinase cause Coffin-Lowry syndrome, highlighting its essential role in skeletal development and cognitive function.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, nucleoli & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3221/91_C11_2_selected.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3221/9882_A_8_8.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3221/9882_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3221/9882_A_8_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3221/9882_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3221/9882_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3221/9882_A_6_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (Hep G2)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177189-RPS6KA3
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- RPS6KA3
- Species Reactivity
- Human, Mouse, Rat
- Clone
- AibG-Rb-PS337
- Applications
- Western Blot (WB), Immunohistochemistry (IHC)
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Concentration
- 0.3 mg/mL
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 40% Glycerol and 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (WB): 1/2000
Immunohistochemistry (IHC): 1/20
Target
- Alternative Names
- Ribosomal Protein S6 Kinase A3; MAP Kinase-Activated Protein Kinase 1b; Insulin-Stimulated Protein Kinase 1; MAPK-Activated Protein Kinase 1b; Ribosomal S6 Kinase 2; MAPKAP Kinase 1b; S6K-Alpha-3; EC 2.7.11.1; MAPKAPK-1b; P90-RSK 3; MAPKAPK1B; Pp90RSK2; ISPK-1; RSK-2; RSK2;
- Gene ID
- 6197
- UniProt ID
- P51812
- Long Name
- Ribosomal Protein S6 Kinase A3
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "RPS6KA3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3927z | Mouse Anti-RPS6KA3 Recombinant Antibody (clone 18G7) | WB, ELISA, FC, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3123 | Hi-Affi™ Recombinant Rabbit Anti-RPS6KA3 Monoclonal Antibody (DS3123AB) | WB, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX984 | Mouse Anti-RPS6KA3 Recombinant Antibody (clone 5H5-C11-F10) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY1386 | Mouse Anti-RPS6KA3 Recombinant Antibody (clone 356CT10.6.1.2) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY1282 | Recombinant Rabbit Anti-RPS6KA3 (phospho Ser227) Antibody (clone R01-5B5) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY1283 | Recombinant Rabbit Anti-RPS6KA3 Antibody (clone R05-6E3) | WB, IHC-P, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6224 | Anti-RPS6KA3 Immunohistochemistry Kit | IHC |
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