Rabbit Anti-RRM1 Recombinant Antibody (VS13-YC1020) (CAT#: VS13-YC1020)
The Rabbit Anti-RRM1 Recombinant Antibody is specific for human RRM1. RRM1 encodes the catalytic subunit of ribonucleotide reductase, essential for DNA replication and repair, with multiple transcript variants observed. The anti-RRM1 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100), Immunofluorescence (1/50-1/200), Immunoprecipitation (1/20).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57265/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57265/if_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows cytoplasmic positivity in germinal center.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57265/137943_A_5_8_selected.jpg
(Immunohistochemical staining of human tonsil shows cytoplasmic positivity in germinal center.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57265/137943_A_5_8_selected.jpg
Figure 3 Tonsil.
(High expression in tonsil)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_A_6_8_val_selected.jpg
(High expression in tonsil)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_A_6_8_val_selected.jpg
Figure 4 Testis
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_A_4_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_A_4_6.jpg
Figure 5 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_A_8_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_A_8_8.jpg
Figure 6 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_B_8_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22093/58719_B_8_5.jpg
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167325-RRM1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167325-RRM1
Specifications
- Immunogen
- Recombinant human RRM1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human RRM1
- Species Reactivity
- Human
- Applications
- WB, IHC-Fr, IHC-P, ICC, IF, IP
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunofluorescence (IF): 1/50-1/200
Immunoprecipitation (IP): 1/20
Target
- Alternative Names
- Ribonucleotide Reductase Catalytic Subunit M1; Ribonucleoside-Diphosphate Reductase Subunit M1; Ribonucleotide Reductase M1 Polypeptide; EC 1.17.4.1; RR1; Ribonucleoside-Diphosphate Reductase Large Subunit;
- Gene ID
- 6240
- UniProt ID
- P23921
- Long Name
- Ribonucleotide Reductase Catalytic Subunit M1
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2841z | Mouse Anti-RRM1 Recombinant Antibody (clone 41D1) | WB, ICC, IF, IHC | Mouse IgG1 |
| MOB-0822MZ | Recombinant Mouse Anti-Human RRM1 Antibody | WB | Mouse antibody |
| ZG-0194U | Mouse Anti-RRM1 Recombinant Antibody (clone 3D6H5) | ELISA, IHC | Mouse IgG |
| VS7-0425-WR796 | Mouse Anti-RRM1 Recombinant Antibody (clone 2D6D8) | WB, IHC, FC | Mouse IgG2a |
| VS7-0425-WR797 | Mouse Anti-RRM1 Recombinant Antibody (clone 5F12E6) | WB, FC | Mouse IgG2a |
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