This product is an antibody that recognizes RSV. The antibody RB1 can be used for immunoassay techniques such as: ELISA, Neut.
Figure 1 In vitro binding and neutralization.
The neutralization activity of RB1 against laboratory strains HMPV A and B with MPE8 control antibody. Assays were run in triplicate, showing error bars at mean with standard deviation (SD).
Figure 2 Efficacy of RB1 in the lower respiratory tracts of cotton rats.
Cotton rats were administered RB1 by intramuscular injection with a dose titration and blood was collected for evaluation of serum antibody concentrations the following day. Immediately after blood sample collections, each animal was challenged intra-nasally with 1x 10̶⁵ pfu of RSV A2 or B 18537 strains. Four days post-challenge, animals were euthanized, blood collected for evaluation of antibody concentrations, and lung tissue collected to assess mAb efficacy by measuring RSV infectious titers in the pulmonary tissues.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
For research use only. Not intended for any clinical use.