Rabbit Anti-SATB2 Recombinant Antibody (clone R06-6D8)
CAT#: VS3-XY3494
The antibody is a recombinant rabbit antibody against SATB2 (SATB homeobox 2), which acts as a docking site for several chromatin remodeling enzymes. SATB2 also acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. This antibody specifically reacts with human, mouse and rat SATB2. It has been detected by Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry or Immunofluorescence.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29543/if_selected.jpg
❮
❯
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat SATB2
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R06-6D8
- Applications
- WB, IHC-P, ICC, IF
- Related Disease
- Glass Syndrome; Cleft Palate, Isolated
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
Target
- Alternative Names
- GLSS; DEL2Q32Q33; C2DELq32q33
- Gene ID
- 23314
- UniProt ID
- Q9UPW6
- Long Name
- SATB homeobox 2
- Cellular Localization
- Nucleus matrix
- Post Translation Modifications
- Sumoylated by PIAS1.
Sumoylation promotes nuclear localization, but represses transcription factor activity.
(Q9UPW6-SATB2_HUMAN)
Ubiquitination at Lys184 (NX_Q9UPW6 [NX_Q9UPW6-1])
Modification sites at PhosphoSitePlus (Q9UPW6)
Glycosylation from GlyGen (Q9UPW6) 3 sites, 1 O-linked glycan (3 sites)
- Protein Refseq
- XP_047299731.1
- Function
- Binds to DNA, at nuclear matrix- or scaffold-associated regions.
Thought to recognize the sugar-phosphate structure of double-stranded DNA.
Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling.
Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers.
Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS3-XY3494. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "SATB2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-888-F(E) | Recombinant Anti-human SATB2 Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| MHH-888-F(E) | Recombinant Human Anti-human SATB2 Antibody Fab Fragment | IP, Neut, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-888-S(P) | Recombinant Anti-human SATB2 Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| MHH-888-S(P) | Recombinant Human Anti-human SATB2 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-888 | Recombinant Human Anti-human SATB2 Antibody | IF, FC, Biosensors, FuncS | IgG |
| VS3-QX1000 | Mouse Anti-SATB2 Recombinant Antibody (clone 4G03) | WB, IP, IF | Mouse IgG1 |
| VS3-FY1624 | Rabbit Anti-SATB2 Recombinant Antibody (clone R02-1H5) | WB | Rabbit IgG |
| VS7-0425-WR828 | Mouse Anti-SATB2 Recombinant Antibody (clone 7B2E11) | IHC, FC | Mouse IgG1 |
| VS7-0425-WR829 | Mouse Anti-SATB2 Recombinant Antibody (clone 7B2C4) | IHC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3175 | Hi-Affi™ Recombinant Rabbit Anti-SATB2 Monoclonal Antibody (DS3175AB) | WB, IP, IHC-P, ICC, IF, IHC-Fr | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC1038 | CytoStream™ Rabbit Anti-SATB2 Recombinant Antibody (VS13-YC1038) | WB, ICC, IF, IHC-P, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6356 | Anti-SATB2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6357 | Anti-Mouse SATB2 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB
Application: ELISA, Inhib, FuncS
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: Block, Cyt, FuncS, Inhib
Application: WB, ELISA, FuncS
Application: ELISA, IP, WB, IHC, IF, FuncS
Application: ELISA, Inhib, FuncS
Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: Block, Cyt, FuncS, Inhib
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
