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For Research Use Only. Not For Clinical Use.
Disease related genes, Human disease related genes, Transcription factors
Intracellular
Cell type enhanced (Excitatory neurons, Distal enterocytes, Enteroendocrine cells, Undifferentiated cells, Paneth cells, Intestinal goblet cells)
Not detected in immune cells
Cell line enhanced (HEL, K-562, THP-1)
Interacts with ATF4 and RUNX2; resulting in enhanced DNA binding and transactivation by these transcription factors (By similarity). Interacts with PIAS1.
Chromatin regulator, Developmental protein, DNA-binding, Repressor