Human Anti-SLC1A5 Recombinant Antibody Hexamer (VS-0924-YC150), CDC Enhanced (CAT#: VS-0924-YC150)

• Immunogen
• Human ASCT2

• Host Species
• Human

• Derivation
• Humanized

• Type
• Antibody hexamer

• Specificity
• Human and Cynomolgus SLC1A5

• Species Reactivity
• Human, Cynomolgus

• Molecule Class
• ~ 900 kDa

• Applications
• Cyt, FC, CDC

• Conjugate
• None

• Related Disease
• Cancer

• Clonality
• Monoclonal

• Purification
• Protein A purified

• Purity
• >95% determined as SDS-PAGE and SEC-HPLC

• Aggregation
• <5%

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.

• Alternative Names
• Solute Carrier Family 1 Member 5; Solute Carrier Family 1 (Neutral Amino Acid Transporter), Member 5; Sodium-Dependent Neutral Amino Acid Transporter Type 2; RD114/Simian Type D Retrovirus Receptor; Baboon M7 Virus Receptor; ATB(0); ASCT2; M7V1; RDRC

• Gene ID
• 6510

• UniProt ID
• Q15758

• Long Name
• Solute Carrier Family 1 Member 5

• Sequence Similarities
• Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A5 subfamily.

• Cellular Localization
• Cell membrane; Multi-pass membrane protein
  Melanosome

• Post Translation Modifications
• Glycosylation at Asn212 and Asn163 ( NX_Q15758 [NX_Q15758-1] )
  Ubiquitination at Lys372, Lys502, Lys522, and Lys537 ( NX_Q15758 [NX_Q15758-1] )

• Function
• Sodium-coupled antiporter of neutral amino acids.
  (Microbial infection) Acts as a cell surface receptor for Feline endogenous virus RD114. AAAT_HUMAN,Q15758
  (Microbial infection) Acts as a cell surface receptor for Baboon M7 endogenous virus. AAAT_HUMAN,Q15758
  (Microbial infection) Acts as a cell surface receptor for type D simian retroviruses. AAAT_HUMAN,Q15758

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