Mouse Anti-SLC1A5 Recombinant Antibody Hexamer (VS-0924-YC151), CDC Enhanced (CAT#: VS-0924-YC151)

The product is a mouse anti-SLC1A5 antibody hexamer with enhanced complement-dependent cytotoxicity (CDC) activity. This hexameric IgG1 targets human SLC1A5 and includes hexamerization-enhancing mutations that promote hexamer formation for optimal C1q binding, thereby boosting CDC activity.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • N-terminal peptide of human ASCT2 with KLH
  • Host Species
  • Mouse
  • Type
  • Antibody hexamer
  • Specificity
  • Human SLC1A5
  • Species Reactivity
  • Human
  • Molecule Class
  • ~ 900 kDa
  • Applications
  • ELISA, CDC
  • Conjugate
  • None
  • Related Disease
  • Cancer

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein G purified
  • Purity
  • >95% determined as SDS-PAGE and SEC-HPLC
  • Aggregation
  • <5%
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • SLC1A5; solute carrier family 1 (neutral amino acid transporter), member 5; R16; AAAT; ATBO; M7V1; RDRC; ASCT2; M7VS1; neutral amino acid transporter B(0); ATB(0); RD114 virus receptor; baboon M7 virus receptor; neutral amino acid transporter B; solute carrier family 1 member 5; RD114/simian type D retrovirus receptor; sodium-dependent neutral amino acid transporter type 2
  • Long Name
  • Solute Carrier Family 1 Member 5
  • Sequence Similarities
  • Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A5 subfamily.
  • Cellular Localization
  • Cell membrane; Multi-pass membrane protein
    Melanosome
  • Post Translation Modifications
  • Glycosylation at Asn212 and Asn163 ( NX_Q15758 [NX_Q15758-1] )
    Ubiquitination at Lys372, Lys502, Lys522, and Lys537 ( NX_Q15758 [NX_Q15758-1] )
  • Function
  • Sodium-coupled antiporter of neutral amino acids.
    (Microbial infection) Acts as a cell surface receptor for Feline endogenous virus RD114. AAAT_HUMAN,Q15758
    (Microbial infection) Acts as a cell surface receptor for Baboon M7 endogenous virus. AAAT_HUMAN,Q15758
    (Microbial infection) Acts as a cell surface receptor for type D simian retroviruses. AAAT_HUMAN,Q15758

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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