Anti-Human SLC1A5 Recombinant Antibody (TAB-1004CLV)
CAT#: TAB-1004CLV
The anti-SLC1A5 antibody is a recombinant mouse antibody that recognizes SLC1A5. The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography. The antibody has been tested in some applications including FC, Inhib.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35239/373_G10_1_selected.jpg
Normal Tissue
Figure 2 Salivary gland
High expression in salivary gland
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_B_3_1_val_selected.jpg
Normal Tissue
Figure 3 Epididymis
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_2_6.jpg
Normal Tissue
Figure 4 Lymph node
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_9_8.jpg
Normal Tissue
Figure 5 Colon
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_7_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Collecting ducts Staining: Low Intensity: Moderate Quantity: <25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35240/70074_A_9_5.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105281-SLC1A5
❮
❯
Specifications
- Immunogen
- Human ASCT2-myc/His (Extracellular Region of ASCT2)
- Host Species
- Mouse
- Specificity
- Human
- Applications
- FC, Inhib
- Related Disease
- Cancer
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry and Inhibition.
Target
- Alternative Names
- SLC1A5; solute carrier family 1 (neutral amino acid transporter), member 5; R16; AAAT; ATBO; M7V1; RDRC; ASCT2; M7VS1; neutral amino acid transporter B(0); ATB(0); RD114 virus receptor; baboon M7 virus receptor; neutral amino acid transporter B; solute carrier family 1 member 5; RD114/simian type D retrovirus receptor; sodium-dependent neutral amino acid transporter type 2
- Gene ID
- 6510
- UniProt ID
- Q15758
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for TAB-1004CLV. Click the button above to contact us or submit your feedback about this product.
Vital for Cancer Research
This antibody has been fundamental in dissecting the metabolic pathways of tumor cells in our lab. It provided us with unparalleled insights into how SLC1A5 facilitates nutrient uptake, directly impacting our understanding of cancer progression and possible points of intervention.
Great Tool for Analytical Studies
The functional inhibition capabilities of the Anti-Human SLC1A5 Recombinant Antibody are impressive. Its role in flow cytometry provided clear data on cellular nutrient uptake processes, advancing our research in metabolic dependencies of aggressive cancer types.
Great Support and Delivery Service
Creative Biolabs provided exceptional support during our initial product inquiries, and the delivery service was prompt. This excellent after-sales service, combined with the antibody's robust functionality, means we'll continue relying on them for our research needs.
Q&As
-
What are the scientific applications of the Anti-Human SLC1A5 Recombinant Antibody?
A: This antibody is primarily used in flow cytometry and inhibition assays. Its specificity for the SLC1A5 protein makes it an effective tool for studying neutral amino acid transport mechanisms, particularly in cancer research frameworks. Researchers can utilize it to investigate SLC1A5's role in cellular nutrient uptake and its implications in tumor growth and metabolism.
-
What pathways associated with SLC1A5 are important for research?
A: SLC1A5 is linked to pathways involved in nutrient uptake and metabolic reprogramming, often hijacked by cancer cells. Studying these pathways helps uncover mechanisms of therapeutic resistance and identifies potential metabolic vulnerabilities that could be exploited in tumor treatment.
-
In what way does this antibody contribute to cancer therapeutic research?
A: By inhibiting SLC1A5, this antibody offers a pathway to disrupt nutrient uptake in cancer cells, a critical survival mechanism for tumor growth. Investigating this can lead to novel therapeutic strategies focused on starving cancer cells of essential nutrients, thus inhibiting their proliferation.
View the frequently asked questions answered by Creative Biolabs Support.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SLC1A5"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1002CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1002CLV) | ELISA | |
| TAB-1003CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1003CLV) | FC, Inhib | |
| TAB-1005CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1005CLV) | FC, Inhib | |
| TAB-1006CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1006CLV) | FC, Inhib | |
| TAB-1007CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1007CLV) | FC, Inhib |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1009CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1009CLV) | FC, ADCC, CDC, Inhib | Chimeric antibody (mouse/human) |
| TAB-1010CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1010CLV) | FC, ADCC, CDC | Chimeric antibody (mouse/human) |
| TAB-1011CLV | Anti-Human SLC1A5 Recombinant Antibody (TAB-1011CLV) | FC, ADCC, CDC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0245-YC | Human Anti-SLC1A5 Recombinant Antibody (HPAB-N0245-YC) | Cyt, FC, FuncS | Humanized IgG |
| VS13-YC1063 | Rabbit Anti-SLC1A5 Recombinant Antibody (VS13-YC1063) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0245-YC-S(P) | Human Anti-SLC1A5 Recombinant Antibody; scFv Fragment (HPAB-N0245-YC-S(P)) | Cyt, FC, FuncS | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0245-YC-F(E) | Human Anti-SLC1A5 Recombinant Antibody; Fab Fragment (HPAB-N0245-YC-F(E)) | Cyt, FC, FuncS | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC150 | Human Anti-SLC1A5 Recombinant Antibody Hexamer (VS-0924-YC150), CDC Enhanced | Cyt, FC, CDC | Antibody hexamer |
| VS-0924-YC151 | Mouse Anti-SLC1A5 Recombinant Antibody Hexamer (VS-0924-YC151), CDC Enhanced | ELISA, CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2087 | Anti-SLC1A5 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6645 | Anti-Human SLC1A5 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC280 | Recombinant Anti-SLC1A5 Vesicular Antibody, EV Displayed (VS-0425-YC280) | ELISA, FC, Cell-uptake |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: IHC, ELISA, FC, WB, ADCC, FuncS
-3.jpg)
-2.png)
Application: WB, ELISA
Application: ELISA, FC, IHC, Neut
Application: FC, IA, IF, IP, IHC, FuncS
Application: ELISA, WB, Microarray, Block
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
