AbPlus™ Anti-STAT5a Magnetic Beads (VS-0724-YC470)
CAT#: VS-0724-YC470
The AbPlus Anti-STAT5a Magnetic Beads (VS-0724-YC470) is an innovative affinity resin which is bound with anti-STAT5a specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of STAT5a protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows strong nuclear positivity in non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42128/ihc_selected.jpg
Normal Tissue
Figure 2 Soft tissue
Peripheral nerve
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3860/11333_B_2_8.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3860/11333_A_8_8.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (HDLM-2, HEL, HMC-1, K-562, MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000126561-STAT5A/subcellular
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-STAT5a specific antibody
- Target
- STAT5a
- Immunogen
- Synthetic peptide corresponding to the C-terminus of the human STAT5a.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
- Alternative Names
- MGF; STAT5
- Gene ID
- 6776
- UniProt ID
- P42229
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "STAT5A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2044z | Mouse Anti-STAT5A Recombinant Antibody (clone 30F6) | WB, FC, ICC, IF, IHC | Mouse IgG1 |
| MRO-1441-CN | Recombinant Rabbit Anti-STAT5A Monoclonal Antibody (CBACN-532) | WB, IF, IHC, IP, FC | Rabbit IgG |
| MRO-2387-CN | Recombinant Rabbit Anti-STAT5A (phosphorylated Tyr694) Monoclonal Antibody (CBACN-672) | WB, IHC | Rabbit IgG |
| ZG-0585U | Rabbit Anti-Phospho-STAT5A (Y694) Recombinant Antibody (clone 3F1) | ELISA, WB, IHC | Rabbit IgG |
| VS3-QX1069 | Mouse Anti-STAT5A Recombinant Antibody (clone 5C10-D3-D10) | WB | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3429 | Hi-Affi™ Recombinant Rabbit Anti-STAT5A Monoclonal Antibody (DS3429AB) | WB, IHC-P, ICC, IF, FC, IP | IgG |
| MOR-4712 | Hi-Affi™ Recombinant Rabbit Anti-STAT5A Monoclonal Antibody (TH226DS) | WB, IF, ICC, IHC-P, FC, ChIP | IgG |
| MOR-4743 | Hi-Affi™ Recombinant Rabbit Anti-STAT5A Monoclonal Antibody (TH257DS) | WB, FC, ChIP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2197 | Anti-STAT5A Immunohistochemistry Kit | IHC | |
| VS-0525-XY6957 | Anti-Mouse STAT5A Immunohistochemistry Kit | IHC | |
| VS-0525-XY6956 | Anti-Human STAT5A Immunohistochemistry Kit | IHC | |
| VS-0525-XY6958 | Anti-Rat STAT5A Immunohistochemistry Kit | IHC |
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