Mouse Anti-SUMO1 Recombinant Antibody (VS3-CJ4)
CAT#: VS3-CJ4
This product is a mouse antibody that recognizes SUMO1.
Specifications
- Immunogen
- Recombinant full length of human SUMO1
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human SUMO1
- Species Reactivity
- Human
- Applications
- WB, ELISA
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein G affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- 1 mg/mL (lot specific)
- Buffer
- 50% Glycerol, 1% BSA, PBS, pH7.4.
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in ELISA (1:5000-1:20000), Western Blot (1:100-1:2000).
Target
- Alternative Names
- DAP1; GMP1; PIC1; SMT3; UBL1; OFC10; SENP2; SMT3C; SMT3H3
- Gene ID
- 7341
- UniProt ID
- P63165
- Sequence Similarities
- Belongs to the ubiquitin family. SUMO subfamily.
- Cellular Localization
- Cytoplasm, Cell membrane, Nucleus
- Post Translation Modifications
- Cleavage of precursor form by SENP1 or SENP2 is necessary for function.
Polymeric SUMO1 chains undergo polyubiquitination by RNF4.
- Protein Refseq
- NP_001005781.1; NP_001005782.1; NP_003343.1
- Function
- Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1; this modulates the gating characteristics of KCNB1 (PubMed:19223394).
Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development. Covalently attached to ZFHX3 (PubMed:24651376).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "SUMO1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0413ZL | Goat anti-Human SUMO-1 Antibody | WB, IP, IF, ELISA | |
| MOB-603NL | Recombinant Anti-Human SUMO1 Antibody | WB, ELISA | |
| MOB-1981CT | Recombinant Mouse anti-Human SUMO1 Monoclonal antibody (opof) | ICC, IF, IP, WB | |
| VS3-QX1074 | Mouse Anti-SUMO1 Recombinant Antibody (clone 6C9-E9-D7) | WB, IHC, FC | Mouse IgG1 |
| VS3-QX1075 | Mouse Anti-SUMO1 Recombinant Antibody (clone 66AT1320) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3460 | Hi-Affi™ Recombinant Rabbit Anti-SUMO1 Monoclonal Antibody (DS3460AB) | WB, IHC-P, ICC, IF, FC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1166 | AbPlus™ Anti-SUMO1 Magnetic Beads (VS-0724-YC1166) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY496 | Rabbit Anti-NHP SUMO1 Recombinant Antibody (VS-1024-XY496) | WB, IHC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC1130 | CytoStream™ Rabbit Anti-SUMO1 Recombinant Antibody (VS13-YC1130) | WB, ICC, IF, IHC-P, IP, FC, ChIP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2228 | Anti-SUMO1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7021 | Anti-Mouse SUMO1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7020 | Anti-Human SUMO1 Immunohistochemistry Kit | IHC |
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