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SUMO1
Anti-SUMO1 Recombinant Antibody Products
- Recombinant Anti-SUMO-1 Antibody (MOB-0267MC)
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- Species Reactivity: Mouse, Rat, Human, Bovine and Porcine
- Application: WB, IP, IF, IHC(P) and ELISA
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- Goat anti-Human SUMO-1 Antibody (MOB-0413ZL)
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- Species Reactivity: Mouse, Rat, Human
- Application: WB, IP, IF, ELISA
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- Recombinant Anti-Human SUMO1 Antibody (MOB-603NL)
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- Species Reactivity: Human
- Application: WB, ELISA
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP, FC, ChIP
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- AbPlus™ Anti-SUMO1 Magnetic Beads (VS-0724-YC1166) (VS-0724-YC1166)
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- Target: SUMO1
- Target Species: Human
- Application: IP, Protein Purification
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: WB, IHC, FC
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- Rabbit Anti-SUMO1 Recombinant Antibody (VS3-CJ1101) (VS3-CJ1101)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP, FC, ChIP
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- Rabbit Anti-NHP SUMO1 Recombinant Antibody (VS-1024-XY496) (VS-1024-XY496)
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- Species Reactivity: Human, Mouse, Non-human primate, Rat
- Type: Rabbit IgG
- Application: WB, IHC, IF, IP
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC-P, IP, FC, ChIP
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- Anti-SUMO1 Immunohistochemistry Kit (VS-0325-XY2228)
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- Species Reactivity: Human, Mouse, Rat
- Target: SUMO1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off.
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Covalently attached to KCNB1; UBE2I increases cross-linking with KCNB1 and PIAS1 decreases cross-links with KCNB1 (PubMed:19223394, 15931224). Interacts with SAE2, RANBP2, PIAS1 and PIAS2 (PubMed:10961991, 15608651, 15660128, 16204249, 15931224). Interacts with PRKN (PubMed:16955485). Covalently attached to a number of proteins such as IKFZ1, PML, RANGAP1, HIPK2, SP100, p53, p73-alpha, MDM2, JUN, DNMT3B and TDG (PubMed:10961991, 15931224, 15959518, 17099698). Also interacts with HIF1A, HIPK2, HIPK3, CHD3, EXOSC9, RAD51 and RAD52 (PubMed:10961991, 12565818). Interacts with USP25 (via ts SIM domain); the interaction weakly sumoylates USP25 (PubMed:18538659). Interacts with SIMC1, CASP8AP2, RNF111 AND SOBP (via SIM domains) (PubMed:23086935). Interacts with BHLHE40/DEC1 (PubMed:21829689). Interacts with RWDD3 (PubMed:17956732). Interacts with UBE2I/UBC9 and this interaction is enhanced in the presence of RWDD3 (PubMed:12924945, 17956732). Interacts with MTA1 (PubMed:21965678). Interacts with SENP2 (PubMed:15296745). Interacts with HINT1 (By similarity). (Microbial infection) Interacts with Epstein-barr virus BGLF4. (Microbial infection) Interacts (via N-terminus) with Tula hantavirus nucleoprotein. (Microbial infection) Interacts (via N-terminus) with Hantaan hantavirus nucleoprotein.
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