Rabbit Anti-SYN1 (phospho S9) Recombinant Antibody (VS3-CJ716) (CAT#: VS3-CJ716)
This product is a rabbit antibody that recognizes human, mouse, and rat phospho-SYN1 (S9).
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Custom Production
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Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21929/48706_B_9_5.jpg
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21929/48706_B_9_5.jpg
Figure 2 RNA cell line category: Cell line enhanced (HaCaT, HHSteC, NTERA-2, SCLC-21H, SH-SY5Y, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000008056-SYN1/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000008056-SYN1/subcellular
Specifications
- Immunogen
- Synthetic peptide conjugated to Keyhole Limpet Haemocyanin (KLH)
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat phospho-SYN1 (S9)
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunohistochemistry.
Target
- Alternative Names
- SYNI; EPILX; MRX50; SYN1a; SYN1b
- Gene ID
- 6853
- UniProt ID
- P17600
- Sequence Similarities
- Belongs to the synapsin family.
- Cellular Localization
- Cell projection, Cytoplasmic vesicle, Golgi apparatus, Synapse
- Post Translation Modifications
- Substrate of different protein kinases. Phosphorylated by CaMK2 and MAPK1 (PubMed:21441247).
Phosphorylation, including phosphorylation at Ser-9, promotes synapsin-1 dissociation from synaptic vesicles, regulates its rate of dispersion, and controls the kinetics of vesicle pool turnover and neurotransmitter release (By similarity) (PubMed:21441247).
- Protein Refseq
- NP_008881.2; NP_598006.1
- Function
- Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal (PubMed:21441247, PubMed:23406870).
Also involved in the regulation of axon outgrowth and synaptogenesis (By similarity).
The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level (By similarity).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "SYN1"
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1979MZ | Recombinant Mouse Anti-Human SYN1 Antibody | WB | Mouse antibody |
| MRO-2388-CN | Recombinant Rabbit Anti-SYN1 (phosphorylated Ser9) Monoclonal Antibody (CBACN-673) | WB, IHC | Rabbit IgG |
| VS3-WK1977 | Rabbit Anti-SYN1 (pS9) Recombinant Antibody (clone R06-7B8) | WB, IHC-P | Rabbit IgG |
| VS7-0425-WR942 | Mouse Anti-SYN1 Recombinant Antibody (clone 7B1D9) | WB, ICC | Mouse IgG1 |
| VS7-0425-WR943 | Mouse Anti-SYN1 Recombinant Antibody (clone 7H10G6) | WB, IHC, ICC, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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