Rabbit Anti-SYN1 (phospho S9) Recombinant Antibody (VS3-CJ716) (CAT#: VS3-CJ716)
This product is a rabbit antibody that recognizes human, mouse, and rat phospho-SYN1 (S9).
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Custom Production
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Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21929/48706_B_9_5.jpg
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21929/48706_B_9_5.jpg
Figure 2 RNA cell line category: Cell line enhanced (HaCaT, HHSteC, NTERA-2, SCLC-21H, SH-SY5Y, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000008056-SYN1/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000008056-SYN1/subcellular
Specifications
- Immunogen
- Synthetic peptide conjugated to Keyhole Limpet Haemocyanin (KLH)
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat phospho-SYN1 (S9)
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunohistochemistry.
Target
- Alternative Names
- SYNI; EPILX; MRX50; SYN1a; SYN1b
- Gene ID
- 6853
- UniProt ID
- P17600
- Sequence Similarities
- Belongs to the synapsin family.
- Cellular Localization
- Cell projection, Cytoplasmic vesicle, Golgi apparatus, Synapse
- Post Translation Modifications
- Substrate of different protein kinases. Phosphorylated by CaMK2 and MAPK1 (PubMed:21441247).
Phosphorylation, including phosphorylation at Ser-9, promotes synapsin-1 dissociation from synaptic vesicles, regulates its rate of dispersion, and controls the kinetics of vesicle pool turnover and neurotransmitter release (By similarity) (PubMed:21441247).
- Protein Refseq
- NP_008881.2; NP_598006.1
- Function
- Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal (PubMed:21441247, PubMed:23406870).
Also involved in the regulation of axon outgrowth and synaptogenesis (By similarity).
The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level (By similarity).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
Rabbit Monoclonal Antibodies
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1979MZ | Recombinant Mouse Anti-Human SYN1 Antibody | WB | Mouse antibody |
| MRO-2388-CN | Recombinant Rabbit Anti-SYN1 (phosphorylated Ser9) Monoclonal Antibody (CBACN-673) | WB, IHC | Rabbit IgG |
| VS-0223-WK65 | Rabbit Anti-SYN1 Recombinant Antibody (VS-0223-WK65) | WB, IP, IHC, IHC-P | Rabbit IgG |
| VS-0223-WK66 | Guinea pig Anti-SYN1 Recombinant Antibody (VS-0223-WK66) | WB, ICC, IHC, IHC-P | Guinea pig IgG |
| VS3-WK1977 | Rabbit Anti-SYN1 (pS9) Recombinant Antibody (clone R06-7B8) | WB, IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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