Rabbit Anti-TAGLN Recombinant Antibody (clone R02-8A4) (CAT#: VS3-XY3517)
This is a recombinant rabbit antibody that specifically recognizes human TAGLN (Transgelin), which involves in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. The antibody has been reported for use in Western Blot and Immunohistochemistry-Paraffin.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/235_G3_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/235_G3_2_selected.jpg
Figure 1 Colon
(Enterocytes - Peripheral nerve/ganglion Staining: Low Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_9_3.jpg
(Enterocytes - Peripheral nerve/ganglion Staining: Low Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_9_3.jpg
Figure 2 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_6_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_6_6.jpg
Figure 3 High expression in smooth muscle
(Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_B_4_7.jpg
(Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_B_4_7.jpg
Figure 4 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+ SV40 Large T+, CACO-2, EFO-21, fHDF/TERT166, hTERT-RPE1, LHCN-M2, U-138 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149591-TAGLN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149591-TAGLN
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human TAGLN
- Species Reactivity
- Human
- Clone
- R02-8A4
- Applications
- WB, IHC-P
- Related Disease
- Peyronie Disease; Aortic Dissection
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
Target
- Alternative Names
- SM22; SMCC; TGLN; TAGLN1; WS3-10; SM22-alpha
- Gene ID
- 6876
- UniProt ID
- Q01995
- Long Name
- Transgelin
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q01995)
Modification sites at neXtProt (NX_Q01995)
Glycosylation from GlyGen (Q01995) 4 sites, 1 O-linked glycan (4 sites)
- Protein Refseq
- NP_003177.2
- Function
- Actin cross-linking/gelling protein (By similarity).
Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1882CT | Recombinant Mouse anti-Human TAGLN Monoclonal antibody (8C8) | ELISA, WB | |
| HPAB-0127-LSX | Human Anti-TAGLN Recombinant Antibody (clone Fab1630) | ELISA, WB | Human IgG |
| FAMAB-1264CQ | Mouse Anti-TAGLN Recombinant Antibody (clone SAIC-33B-129) | WB, Immuno-MRM, ELISA | Mouse IgG1 |
| VS-0923-FY141 | Recombinant Mouse Anti-TAGLN Antibody (VS-0923-FY141) | ELISA, WB | Mouse IgG1 |
| VS13-YC1139 | Rabbit Anti-TAGLN Recombinant Antibody (VS13-YC1139) | IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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