Rabbit Anti-TAGLN Recombinant Antibody (clone R02-8A4)
CAT#: VS3-XY3517
This is a recombinant rabbit antibody that specifically recognizes human TAGLN (Transgelin), which involves in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. The antibody has been reported for use in Western Blot and Immunohistochemistry-Paraffin.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria & microtubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/235_G3_2_selected.jpg
Normal Tissue
Figure 1 Colon
Enterocytes - Peripheral nerve/ganglion Staining: Low Intensity: Weak
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_9_3.jpg
Normal Tissue
Figure 2 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_6_6.jpg
Normal Tissue
Figure 3 High expression in smooth muscle
Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_B_4_7.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+ SV40 Large T+, CACO-2, EFO-21, fHDF/TERT166, hTERT-RPE1, LHCN-M2, U-138 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149591-TAGLN
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human TAGLN
- Species Reactivity
- Human
- Clone
- R02-8A4
- Applications
- WB, IHC-P
- Related Disease
- Peyronie Disease; Aortic Dissection
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
Target
- Alternative Names
- SM22; SMCC; TGLN; TAGLN1; WS3-10; SM22-alpha
- Gene ID
- 6876
- UniProt ID
- Q01995
- Long Name
- Transgelin
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q01995)
Modification sites at neXtProt (NX_Q01995)
Glycosylation from GlyGen (Q01995) 4 sites, 1 O-linked glycan (4 sites)
- Protein Refseq
- NP_003177.2
- Function
- Actin cross-linking/gelling protein (By similarity).
Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
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- Product Name
Recommended Dilution Buffer
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Secondary Antibody
- CAT
- Product Name
See other products for "TAGLN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1882CT | Recombinant Mouse anti-Human TAGLN Monoclonal antibody (8C8) | ELISA, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127-LSX | Human Anti-TAGLN Recombinant Antibody (clone Fab1630) | ELISA, WB | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127-LSX-S(P) | Human Anti-TAGLN Recombinant Antibody (clone Fab1630); scFv Fragment | WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127-LSX-F(E) | Human Anti-TAGLN Recombinant Antibody (clone Fab1630); Fab Fragment | WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1264CQ | Mouse Anti-TAGLN Recombinant Antibody (clone SAIC-33B-129) | WB, Immuno-MRM, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0923-FY141 | Recombinant Mouse Anti-TAGLN Antibody (VS-0923-FY141) | ELISA, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1175 | AbPlus™ Anti-TAGLN Magnetic Beads (VS-0724-YC1175) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC1139 | Rabbit Anti-TAGLN Recombinant Antibody (VS13-YC1139) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2245 | Anti-TAGLN Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7082 | Anti-Mouse TAGLN Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7081 | Anti-Human TAGLN Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7083 | Anti-Rat TAGLN Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7084 | Anti-Porcine TAGLN Immunohistochemistry Kit | IHC |
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