Mouse Anti-Tau Recombinant Antibody (clone Tau5) (CAT#: HPAB-S0178-YC)

The product is a recombinant monoclonal antibody against Human Tau. The antibody can be used in some applications including ELISA assay.


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Figure 1 An anti-tau antibody, Tau5, abrogates the inhibition of LTP by soluble extracts of AD brain.

Figure 1 An anti-tau antibody, Tau5, abrogates the inhibition of LTP by soluble extracts of AD brain.

Tau5 ID decreased both WB and ELISA detected tau in the AD1 extract by> 80%, compared with mock ID with the isotype control mAb 46-4. Tau5 ID abrogated the inhibitory effect of AD1 extract on LTP.

Ondrejcak, T., Klyubin, I., Corbett, G. T., Fraser, G., Hong, W., Mably, A. J., ... & Rowan, M. J. (2018). Cellular prion protein mediates the disruption of hippocampal synaptic plasticity by soluble tau in vivo. Journal of Neuroscience, 38(50), 10595-10606.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human Tau
  • Species Reactivity
  • Human
  • Clone
  • Tau5
  • Applications
  • ELISA
  • Related Disease
  • Alzheimer's disease

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Buffer
  • PBS
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Tau protein

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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