Rabbit Anti-TFF3 Recombinant Antibody (VS13-YC1153) (CAT#: VS13-YC1153)
The Rabbit Anti-TFF3 Recombinant Antibody is specific for human TFF3. TFF3 belongs to the trefoil family, encoding a stable secretory protein acting on gastrointestinal mucosa, expressed in goblet cells, stabilizing mucus layers. The anti-TFF3 antibody can be used for Immunohistochemistry (1/100-1/200).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & nucleoli.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35464/1134_F11_5_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & nucleoli.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35464/1134_F11_5_selected.jpg
Figure 2 Rectum
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35464/165692_A_4_3_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35464/165692_A_4_3_val_selected.jpg
Figure 3 Small intestine
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20681/ihc_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20681/ihc_selected.jpg
Figure 4 Colon
(Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35464/165692_A_7_3.jpg
(Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35464/165692_A_7_3.jpg
Figure 5 RNA cell line category: Cell line enhanced (MCF7, OE19, T-47d, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160180-TFF3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160180-TFF3
Specifications
- Immunogen
- Recombinant human Trefoil Factor 3.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human TFF3
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
- Related Disease
- Intellectual Developmental Disorder
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- Trefoil Factor 3; Trefoil Factor 3 (Intestinal); Polypeptide P1.B; ITF; TFI; Intestinal Trefoil Factor; HP1.B; HITF; P1B;
- Gene ID
- 7033
- UniProt ID
- Q07654
- Long Name
- Trefoil Factor 3
- Cellular Localization
- Cytoplasm; Cytosol; Nucleus
- Protein Refseq
- XP_054183633.1
- Function
- Transcription factor that acts as a master regulator of lysosomal biogenesis and immune response (PubMed:2338243, 24448649, 29146937, 30733432, 31672913, 37079666).
Specifically recognizes and binds E-box sequences (5'-CANNTG-3'); efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF (PubMed:24448649).
Involved in the cellular response to amino acid availability by acting downstream of MTOR: in the presence of nutrients, TFE3 phosphorylation by MTOR promotes its inactivation.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TFF3"
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IgG Antibodies
Rabbit Monoclonal Antibodies
ScFv Antibodies
Fab Antibodies
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0834MZ | Recombinant Mouse Anti-Human TFF3 Antibody | IHC-P | Mouse antibody |
| HPAB-0133-CN | Human Anti-TFF3 Recombinant Antibody (clone 1) | ELISA | Human IgG |
| ZG-0180U | Mouse Anti-TFF3 Recombinant Antibody (clone 1D3G1) | ELISA, IHC, IF | Mouse IgG2a |
| VS3-XY3524 | Rabbit Anti-TFF3 Recombinant Antibody (clone R06-6J1) | WB, IHC-P, IP | Rabbit IgG |
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