Rabbit Anti-TFF3 Recombinant Antibody (VS13-YC1153) (CAT#: VS13-YC1153)

• Immunogen
• Recombinant human Trefoil Factor 3.

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human TFF3

• Species Reactivity
• Human

• Applications
• IHC-P

• Conjugate
• NONE

• Related Disease
• Intellectual Developmental Disorder

• Clonality
• Monoclonal

• Purification
• Affinity Chromatography purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.

• Preservative
• 0.02% Sodium azide

• Storage
• Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Shipping with ice pack.

• Application Notes
• Immunohistochemistry (IHC): 1/100-1/200

• Alternative Names
• Trefoil Factor 3; Trefoil Factor 3 (Intestinal); Polypeptide P1.B; ITF; TFI; Intestinal Trefoil Factor; HP1.B; HITF; P1B;

• Gene ID
• 7033

• UniProt ID
• Q07654

• Long Name
• Trefoil Factor 3

• Cellular Localization
• Cytoplasm; Cytosol; Nucleus

• Protein Refseq
• XP_054183633.1

• Function
• Transcription factor that acts as a master regulator of lysosomal biogenesis and immune response (PubMed:2338243, 24448649, 29146937, 30733432, 31672913, 37079666).
  Specifically recognizes and binds E-box sequences (5'-CANNTG-3'); efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF (PubMed:24448649).
  Involved in the cellular response to amino acid availability by acting downstream of MTOR: in the presence of nutrients, TFE3 phosphorylation by MTOR promotes its inactivation.

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-061CQ
• Sheep Anti-Rabbit IgG (H&L) Antibody

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

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