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TFF3

Anti-TFF3 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Protein class

Cancer-related genes, Plasma proteins

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enriched (Intestinal goblet cells)

Immune cell specificity

Immune cell enriched (eosinophil)

Cell line specificity

Cell line enhanced (MCF7, OE19, T-47d, TIME)

Interaction

Monomer. Homodimer; disulfide-linked.

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