Mouse Anti-TGFB2 Recombinant Antibody (VS3-FY2893)
CAT#: VS3-FY2893
The anti-TGFB2 recombinant monoclonal antibody has been genetically engineered to specifically target human TGFB2 protein, a calculated molecular weight of the protein is about 47.7 kDa. The antibody can be utilized for detection of TGFB2 by Western Blot (1/500-1/1000), Immunohistochemistry (1/50-1/200), Immunocytochemistry (1/10-1/50).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line EFO-21
Immunofluorescent staining of human cell line EFO-21 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6134/2063_C8_2_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (EFO-21, hTERT-RPE1, U-2 OS)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000092969-TGFB2
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human TGFB2
- Species Reactivity
- Human
- Applications
- Western Blot, Immunohistochemistry, Immunocytochemistry
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 47.7 kDa.
- Related Disease
- Loeys-Dietz Syndrome 4 and Familial Thoracic Aortic Aneurysm And Aortic Dissection
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/200
Immunocytochemistry: 1/10-1/50
Target
- Alternative Names
- Transforming Growth Factor Beta 2; Glioblastoma-Derived T-Cell Suppressor Factor; Prepro-Transforming Growth Factor Beta-2; BSC-1 Cell Growth Inhibitor; Polyergin; Cetermin; G-TSF
- Gene ID
- 7042
- UniProt ID
- P61812
- Sequence Similarities
- Belongs to the TGF-beta family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- [Transforming growth factor beta-2 proprotein]: The precursor proprotein is cleaved in the Golgi apparatus to form Transforming growth factor beta-2 (TGF-beta-2) and Latency-associated peptide (LAP) chains, which remain non-covalently linked, rendering TGF-beta-2 inactive. (P61812-TGFB2_HUMAN)
Glycosylation at Asn72, Asn140, and Asn241 (NX_P61812 [NX_P61812-1])
Modification sites at PhosphoSitePlus (P61812)
Glycosylation from GlyConnect TGFB2_HUMAN (1836)
Glycosylation from GlyGen (P61812) 4 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
- Protein Refseq
- NP_003229.1
- Function
- Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains remain non-covalently linked rendering TGF-beta-2 inactive during storage in extracellular matrix (By similarity).
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Related Diseases
Inflammatory Bowel Diseases
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "TGFB2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-100 | Anti-Human TGF beta 2 Recombinant Antibody (TAB-100) | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2017CQ | Rat Anti-Tgfb2 Recombinant Antibody (clone CBL883) | IHC, Neut, WB | Rat IgG2 |
| NEUT-2018CQ | Rat Anti-Tgfb2 Recombinant Antibody (clone CBL649) | Neut | Rat IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0664-YC | Human Anti-TGFB2 Recombinant Antibody (HPAB-M0664-YC) | ELISA, FuncS | Human IgG |
| HPAB-M0665-YC | Human Anti-TGFB2 Recombinant Antibody (HPAB-M0665-YC) | ELISA, FuncS | Human IgG |
| HPAB-M0666-YC | Human Anti-TGFB2 Recombinant Antibody (HPAB-M0666-YC) | ELISA, FuncS | Human IgG |
| HPAB-0665YY | Human Anti-TGFB2 Recombinant Antibody (clone GDF11 Inh-2) | Inhib, ELISA, WB | Human IgG1 |
| HPAB-2108-FY | Human Anti-TGFB2 Recombinant Antibody (clone 6A5) | ELISA | Human IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0664-YC-S(P) | Human Anti-TGFB2 Recombinant Antibody; scFv Fragment (HPAB-M0664-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-M0665-YC-S(P) | Human Anti-TGFB2 Recombinant Antibody; scFv Fragment (HPAB-M0665-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-M0666-YC-S(P) | Human Anti-TGFB2 Recombinant Antibody; scFv Fragment (HPAB-M0666-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-0665YY-S(P) | Human Anti-TGFB2 Recombinant Antibody (clone GDF11 Inh-2); scFv Fragment | Inhib, ELISA, WB | Human scFv |
| HPAB-2108-FY-S(P) | Human Anti-TGFB2 Recombinant Antibody (clone 6A5); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0662-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0662-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0663-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0663-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0664-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0664-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0665-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0665-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0666-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0666-YC-F(E)) | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-100 | Afuco™ Anti-TGFB2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-100) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY188 | Mouse Anti-TGFB2 (clone 6A5) scFv-Fc Chimera | Neut, ELISA | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2277 | Anti-TGFB2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7211 | Anti-Mouse TGFB2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC308 | Recombinant Anti-TGFB2 Eliminating Antibody, pH-Sensitive (VS-0625-YC308) | Antigen-Sweeping In Vivo. | Human IgG4 |
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