Mouse Anti-TGFB2 Recombinant Antibody (VS3-FY2893) (CAT#: VS3-FY2893)
The anti-TGFB2 recombinant monoclonal antibody has been genetically engineered to specifically target human TGFB2 protein, a calculated molecular weight of the protein is about 47.7 kDa. The antibody can be utilized for detection of TGFB2 by Western Blot (1/500-1/1000), Immunohistochemistry (1/50-1/200), Immunocytochemistry (1/10-1/50).
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line EFO-21
(Immunofluorescent staining of human cell line EFO-21 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6134/2063_C8_2_selected.jpg
(Immunofluorescent staining of human cell line EFO-21 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6134/2063_C8_2_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (EFO-21, hTERT-RPE1, U-2 OS)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000092969-TGFB2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000092969-TGFB2
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human TGFB2
- Species Reactivity
- Human
- Applications
- Western Blot, Immunohistochemistry, Immunocytochemistry
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 47.7 kDa.
- Related Disease
- Loeys-Dietz Syndrome 4 and Familial Thoracic Aortic Aneurysm And Aortic Dissection
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/200
Immunocytochemistry: 1/10-1/50
Target
- Alternative Names
- Transforming Growth Factor Beta 2; Glioblastoma-Derived T-Cell Suppressor Factor; Prepro-Transforming Growth Factor Beta-2; BSC-1 Cell Growth Inhibitor; Polyergin; Cetermin; G-TSF
- Gene ID
- 7042
- UniProt ID
- P61812
- Sequence Similarities
- Belongs to the TGF-beta family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- [Transforming growth factor beta-2 proprotein]: The precursor proprotein is cleaved in the Golgi apparatus to form Transforming growth factor beta-2 (TGF-beta-2) and Latency-associated peptide (LAP) chains, which remain non-covalently linked, rendering TGF-beta-2 inactive. (P61812-TGFB2_HUMAN)
Glycosylation at Asn72, Asn140, and Asn241 (NX_P61812 [NX_P61812-1])
Modification sites at PhosphoSitePlus (P61812)
Glycosylation from GlyConnect TGFB2_HUMAN (1836)
Glycosylation from GlyGen (P61812) 4 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
- Protein Refseq
- NP_003229.1
- Function
- Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains remain non-covalently linked rendering TGF-beta-2 inactive during storage in extracellular matrix (By similarity).
Recommended Products
Secondary Antibody
Isotype Control
Related Resources
Inflammatory Bowel Diseases
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1494z | Mouse Anti-TGFB2 Recombinant Antibody (MOB-1494z) | WB, IHC | Mouse IgG2b |
| MOB-2019CT | Recombinant Mouse anti-Human TGFB2 Monoclonal antibody (8607) | IHC-Fr, IHC-P, WB | |
| HPAB-M0662-YC | Human Anti-TGFB2 Recombinant Antibody (HPAB-M0662-YC) | ELISA, FuncS | Human IgG |
| HPAB-0665YY | Human Anti-TGFB2 Recombinant Antibody (clone GDF11 Inh-2) | Inhib, ELISA, WB | Human IgG1 |
| HPAB-2108-FY | Human Anti-TGFB2 Recombinant Antibody (clone 6A5) | ELISA | Human IgG4 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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