Mouse Anti-TGFB2 Recombinant Antibody (VS3-FY2893) (CAT#: VS3-FY2893)

The anti-TGFB2 recombinant monoclonal antibody has been genetically engineered to specifically target human TGFB2 protein, a calculated molecular weight of the protein is about 47.7 kDa. The antibody can be utilized for detection of TGFB2 by Western Blot (1/500-1/1000), Immunohistochemistry (1/50-1/200), Immunocytochemistry (1/10-1/50).

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
RNA Expression

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human TGFB2
  • Species Reactivity
  • Human
  • Applications
  • Western Blot, Immunohistochemistry, Immunocytochemistry
  • Conjugate
  • Unconjugated, FITC
  • MW
  • The molecular weight of the target protein is approximately 47.7 kDa.
  • Related Disease
  • Loeys-Dietz Syndrome 4 and Familial Thoracic Aortic Aneurysm And Aortic Dissection

Product Property

  • Clonality
  • Monoclonal Antibody
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunohistochemistry: 1/50-1/200
    Immunocytochemistry: 1/10-1/50

Target

  • Alternative Names
  • Transforming Growth Factor Beta 2; Glioblastoma-Derived T-Cell Suppressor Factor; Prepro-Transforming Growth Factor Beta-2; BSC-1 Cell Growth Inhibitor; Polyergin; Cetermin; G-TSF
  • Sequence Similarities
  • Belongs to the TGF-beta family.
  • Cellular Localization
  • Secreted
  • Post Translation Modifications
  • [Transforming growth factor beta-2 proprotein]: The precursor proprotein is cleaved in the Golgi apparatus to form Transforming growth factor beta-2 (TGF-beta-2) and Latency-associated peptide (LAP) chains, which remain non-covalently linked, rendering TGF-beta-2 inactive. (P61812-TGFB2_HUMAN)
    Glycosylation at Asn72, Asn140, and Asn241 (NX_P61812 [NX_P61812-1])
    Modification sites at PhosphoSitePlus (P61812)
    Glycosylation from GlyConnect TGFB2_HUMAN (1836)
    Glycosylation from GlyGen (P61812) 4 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
  • Function
  • Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains remain non-covalently linked rendering TGF-beta-2 inactive during storage in extracellular matrix (By similarity).

Recommended Products

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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