Human Anti-TNFRSF4 Recombinant Antibody (clone M/YC-46) (CAT#: HPAB-M0679-YC)
Provided is an anti OX40 antagonist antibody for the treatment of atopic dermatitis, including moderate-to-severe Atopic dermatitis and stable liquid formulations suitable for the treatment of atopic dermatitis and other autoimmune diseases.
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Normal Tissue
RNA Expression
Figure 1 High expression in lymph node.
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16128/35587_A_7_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16128/35587_A_7_8.jpg
Figure 2 Tonsil
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16128/35587_A_6_8.jpg
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16128/35587_A_6_8.jpg
Figure 3 RNA cell line category: Group enriched (MOLT-4, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186827-TNFRSF4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186827-TNFRSF4
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human TNFRSF4
- Species Reactivity
- Human
- Clone
- M/YC-46
- Applications
- ELISA, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TNF Receptor Superfamily Member 4; TAX Transcriptionally-Activated Glycoprotein 1 Receptor; OX40L Receptor; ACT35 Antigen; CD134 Antigen; TXGP1L; Tax-Transcriptionally Activated Glycoprotein 1 Receptor; Tumor Necrosis Factor Receptor Superfamily, Member 4; Tumor Necrosis Factor Receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35;
- Gene ID
- 7293
- UniProt ID
- P43489
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0873CL | Human Anti-TNFRSF4 Recombinant Antibody (TAB-0873CL) | FC, Inhib | Humanized antibody |
| TAB-0876CL | Human Anti-TNFRSF4 Recombinant Antibody (TAB-0876CL) | ELISA, FuncS, FC | Humanized IgG |
| TAB-0880CL | Human Anti-TNFRSF4 Recombinant Antibody (TAB-0880CL) | FC | Humanized antibody |
| TAB-0873CL-F(E) | Human Anti-TNFRSF4 Recombinant Antibody; Fab Fragment (TAB-0873CL-F(E)) | FC | Humanized Fab |
| TAB-0876CL-F(E) | Human Anti-TNFRSF4 Recombinant Antibody; Fab Fragment (TAB-0876CL-F(E)) | ELISA, FC | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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