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    CytoStream™ Mouse Anti-TSC1 Recombinant Antibody (VS13-YC1185) (CAT#: VS13-YC1185)

    The CytoStream™ Mouse Anti-TSC1 Recombinant Antibody is specific for human and mouse TSC1. TSC1 encodes a protein inhibiting growth, linked to tuberin stabilization, with mutations causing tuberous sclerosis, showing spliced variants. The anti-TSC1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/500-1/1000).

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line RH-30
    Figure 1 IF staining of human cell line RH-30
    (Immunofluorescent staining of human cell line RH-30 shows localization to cytosol & lipid droplets.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/74132/1666_F4_31_selected.jpg
    Figure 2 IF staining of human cell line U-251 MG
    Figure 2 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11568/if_selected.jpg
    Normal Tissue
    Figure 3 Lymph node
    Figure 3 Lymph node
    (Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11568/33733_A_9_8.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11568/33733_B_7_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11568/33733_A_8_3.jpg
    Figure 6 Liver
    Figure 6 Liver
    (Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11568/33733_A_9_4.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11568/33733_A_8_5.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000165699-TSC1

    Specifications

    • Immunogen
    • Recombinant human Hamartin, aa 401-600.
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1
    • Specificity
    • Human and Mouse TSC1
    • Species Reactivity
    • Human, Mouse
    • Applications
    • WB, ICC, IF, IHC-P, FC
    • Conjugate
    • NONE

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein G purified
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
    • Preservative
    • 0.05% Sodium azide
    • Storage
    • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Shipping with ice pack.

    Applications

    • Application Notes
    • Western blot (WB): 1/500
      Immunocytochemistry (ICC): 1/100
      Immunohistochemistry-paraffin (IHC-P): 1/200-1/600
      Flow cytometry (FC): 1/500-1/1000

    Target

    • Alternative Names
    • TSC Complex Subunit 1; Tuberous Sclerosis 1 Protein; Hamartin; TSC; Tuberous Sclerosis 1; Tumor Suppressor; KIAA0243; LAM;
    • Long Name
    • TSC Complex Subunit 1
    • Cellular Localization
    • Cytoplasm; Cell membrane

    Recommended Products

    Secondary Antibody

    Isotype Control

    Related Resources

    • Related Signaling Pathways
    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "TSC1"

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    CAT Product Name Application Type
    MOB-3081z Mouse Anti-TSC1 Recombinant Antibody (clone 36H8) WB, FC, IHC Mouse IgG2b
    VS3-XY1551 Mouse Anti-TSC1 Recombinant Antibody (clone 357CT4.4.2) WB Mouse IgG2b
    VS3-FY2908 Mouse Anti-TSC1 Recombinant Antibody (VS3-FY2908) WB Mouse IgG

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