Mouse Anti-VAV1 Recombinant Antibody (VS3-CJ674) (CAT#: VS3-CJ674)
This product is a mouse antibody that recognizes human VAV1.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line THP-1
(Immunofluorescent staining of human cell line THP-1 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5925/2005_D12_1_selected.jpg
(Immunofluorescent staining of human cell line THP-1 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5925/2005_D12_1_selected.jpg
Figure 2 Testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_6_6.jpg
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_6_6.jpg
Figure 3 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_8_8.jpg
(Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_8_8.jpg
Figure 4 Tonsil
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_6_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_6_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (HMC-1, Karpas-707, MOLT-4, REH, THP-1, U-266/84, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000141968-VAV1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000141968-VAV1
Specifications
- Immunogen
- Recombinant protein of human VAV1
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human VAV1
- Species Reactivity
- Human
- Applications
- WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.09% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:4000).
Target
- Alternative Names
- VAV
- Gene ID
- 7409
- UniProt ID
- P15498
- Cellular Localization
- Cell-cell junction, Cytoplasm, Cytosol, Plasma membrane
- Post Translation Modifications
- Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS) (By similarity).
Phosphorylated by FYN.
- Protein Refseq
- NP_001245136.1; NP_005419.2
- Function
- Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Recommended Products
Secondary Antibody
Recommended Dilution Buffer
Related Resources
FcεR1 Signaling Pathway
TCR Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1964z | Mouse Anti-VAV1 Recombinant Antibody (clone 32C6) | WB, ELISA, FC | Mouse IgG1 |
| MOB-1938CT | Recombinant Mouse anti-Human VAV1 Monoclonal antibody (EML2180) | WB | |
| VS3-QX1230 | Mouse Anti-VAV1 Recombinant Antibody (clone 5E7-F8-B9) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS7-0425-WR1106 | Mouse Anti-VAV1 Recombinant Antibody (clone 2E11) | WB, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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