CytoStream™ Rabbit Anti-VAV1 Recombinant Antibody (VS13-YC1211) (CAT#: VS13-YC1211)
The CytoStream™ Rabbit Anti-VAV1 Recombinant Antibody is specific for human VAV1. VAV1, a member of the VAV gene family, is a GEF for Rho GTPases, important in hematopoiesis and T/B cell development and activation. The anti-VAV1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line THP-1
(Immunofluorescent staining of human cell line THP-1 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5925/2005_D12_1_selected.jpg
(Immunofluorescent staining of human cell line THP-1 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5925/2005_D12_1_selected.jpg
Figure 2 Testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_6_6.jpg
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_6_6.jpg
Figure 3 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_8_8.jpg
(Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_8_8.jpg
Figure 4 Tonsil
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_6_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1864/163102_A_6_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (HMC-1, Karpas-707, MOLT-4, REH, THP-1, U-266/84, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000141968-VAV1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000141968-VAV1
Specifications
- Immunogen
- Recombinant human Vav1/2/3.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human VAV1
- Species Reactivity
- Human
- Applications
- WB, ICC, IF, IP, FC
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunofluorescence (IF): 1/50-1/200
Immunoprecipitation (IP): 1/50
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- Vav Guanine Nucleotide Exchange Factor 1; Vav 1 Guanine Nucleotide Exchange Factor; Vav 1 Oncogene; VAV; Proto-Oncogene Vav;
- Gene ID
- 7409
- UniProt ID
- P15498
- Long Name
- Vav Guanine Nucleotide Exchange Factor 1
- Function
- Signal transduction
Recommended Products
Secondary Antibody
Isotype Control
Related Resources
FcεR1 Signaling Pathway
TCR Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1964z | Mouse Anti-VAV1 Recombinant Antibody (clone 32C6) | WB, ELISA, FC | Mouse IgG1 |
| MOB-1938CT | Recombinant Mouse anti-Human VAV1 Monoclonal antibody (EML2180) | WB | |
| VS3-QX1230 | Mouse Anti-VAV1 Recombinant Antibody (clone 5E7-F8-B9) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-CJ674 | Mouse Anti-VAV1 Recombinant Antibody (VS3-CJ674) | WB | Mouse IgG1, κ |
| VS7-0425-WR1106 | Mouse Anti-VAV1 Recombinant Antibody (clone 2E11) | WB, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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