Mouse Anti-VSIR Recombinant Antibody (clone mam82) (CAT#: FAMAB-1490CQ)
This product is a recombinant mouse antibody that recognizes VSIR. The antibody was purified by affinity chromatography. It can be used in Block, ELISA, IHC.
Specific Inquiry
Figure 1 PD-1H inhibits antigen-specific CD4+ T cell responses in vitro.
Proliferation was assessed in the presence of 2 μg/ml of PD-1H mAb or mouse Ig.
Flies, D. B., Han, X., Higuchi, T., Zheng, L., Sun, J., Ye, J. J., & Chen, L. (2014). Coinhibitory receptor PD-1H preferentially suppresses CD4+ T cell–mediated immunity. The Journal of clinical investigation, 124(5), 1966-1975.
Figure 2 PD-1H–deficient mice are more susceptible to acute Con A–induced hepatitis.
C57BL/6 mice were pretreated with i.p. injections of control mouse Ig or anti-PD-1H (mam82) 3 hours before i.v. injections of Con A at 30 mg/kg and monitored for survival.
Flies, D. B., Han, X., Higuchi, T., Zheng, L., Sun, J., Ye, J. J., & Chen, L. (2014). Coinhibitory receptor PD-1H preferentially suppresses CD4+ T cell–mediated immunity. The Journal of clinical investigation, 124(5), 1966-1975.
Specifications
- Immunogen
- Mouse PD-1H Ig fusion protein
- Host Species
- Mouse
- Type
- Mouse IgG1
- Species Reactivity
- Mouse
- Clone
- mam82
- Applications
- Block, ELISA, IHC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- V-Set Immunoregulatory Receptor; V-Set Domain-Containing Immunoregulatory Receptor; V-Domain Ig Suppressor Of T Cell Activation; Stress-Induced Secreted Protein-1; PDCD1 Homolog; C10orf54; Sisp-1; SISP1; VISTA; V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation; Chromosome 10 Open Reading Frame 54;
- Gene ID
- 74048
- UniProt ID
- Q9D659
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2274CQ | Hamster Anti-Vsir Recombinant Antibody (clone MH5A) | FC, Block, IHC, WB | Hamster IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-036LC | Hamster Anti-VSIR Recombinant Antibody (clone YC160) | FuncS, WB | Hamster IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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