Mouse Anti-ZFP36 Recombinant Antibody (VS-0326-YC1159)
CAT#: VS-0326-YC1159
This product is an anti-ZFP36 antibody panel that contains two antibodies targeting human ZFP36. ZFP36 (Tristetraprolin/TTP) is an RNA-binding protein that regulates the stability of mRNAs containing AU-rich elements (AREs), such as TNF-α. It recruits the deadenylation machinery to trigger mRNA decay. ZFP36 signaling acts as a powerful anti-inflammatory "brake"; its loss leads to systemic inflammatory syndrome due to the overproduction of pro-inflammatory cytokines. Two monoclonal antibodies, VS-0326-YC383 and VS-0326-YC384, directed against ZFP36 were used for in vitro assays including Immunohistochemistry (IHC), Immunoprecipitation (IP) and Western Blot (WB).
| Sub Cat | Clone | Species Reactivity | Applications | Application Notes | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS-0326-YC383 | ZF383 | Human | IP, WB | WB (1/500-1/1000), IP (1/100-1/200) | ||||||
| VS-0326-YC384 | ZF384 | Human | IHC | IHC (1/100-1/200) |
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human ZFP36
- Conjugate
- The unconjugated, Biotin and FITC formats are available.
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Target
- Alternative Names
- ZFP36 Ring Finger Protein; Tristetraprolin; Growth Factor-Inducible Nuclear Protein NUP475; G0/G1 Switch Regulatory Protein 24; RNF162A; Zfp-36; NUP475; G0S24; TTP; Zinc Finger Protein 36, C3H Type, Homolog (Mouse);Zinc Finger Protein 36, C3H Type, Homolog; Zinc Finger Protein, C3H Type, 36 Homolog; MRNA Decay Activator Protein ZFP36; Zinc Finger Protein 36 Homolog; Zinc Finger Protein 36; Tristetraproline; TIS11A; GOS24; TIS11;
- Gene ID
- 7538
- UniProt ID
- P26651
- Long Name
- ZFP36 Ring Finger Protein
- Post Translation Modifications
- Unmodified
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "ZFP36"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3420 | PE-B8/Human ZFP36 (HPKYKTEL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3421 | APC-B8/Human ZFP36 (HPKYKTEL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2529 | Anti-ZFP36 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY8021 | Anti-Mouse ZFP36 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY8020 | Anti-Human ZFP36 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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