BV421-DRB1*04:05/Human CEA (LWWVNNQSLPVSP) MHC Tetramer (CAT#: MHC-YF1482)

This product is a MHC tetramer of biotinylated peptide/MHC complex composed CEA-derived peptide of LWWVNNQSLPVSP sequence covering 321-333 and DRB1*04:05 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • DRB1*04:05
  • Class
  • Class II
  • MHC Species
  • Human
  • Antigen
  • CEA
  • Antigen Species
  • Human
  • Peptide
  • LWWVNNQSLPVSP
  • Range
  • 321-333
  • Conjugate
  • BV421
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • CEA; CD66e

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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