anti-HIgG(Fc)-C-PNU ADC
CAT#: ADC-1007-SHz
This ADC product is composed of an anti-human IgG Fc specific polyclonal antibody conjugated via a cleavable linker to PNU-159682 (anti-human IgG(Fc)-CL-PNU). The antibody portion is a secondary antibody and the drug portion, PNU-159682, is a derivative of nemorubicin which causes cell death by intercalating DNA and inhibiting replication. This product displays no obvious toxicity without a primary antibody and can be a quite efficient and economical alternative to pre-screening human monoclonal antibodies as ADC candidates.
Specifications
- Antibody Overview
- anti-human IgG Fc specific polyclonal IgG antibody
- Antibody Isotype
- IgG
- Linker
- CL
- Linker Class/Description
- Class: Cleavable linkers
Description: Cleavable linkers rely on processes inside the cell to liberate the toxin, such as reduction in the cytoplasm, exposure to acidic conditions in the lysosome, or cleavage by specific proteases within the cell.
- Drug
- PNU-159682
- Drug Class/Description
- Class: Nemorubicin
Description: Nemorubicin is a 3'-deamino-3'[2-(S)-methoxy-4-morpholinyl] derivative of doxorubicin. Doxorubicin is the generic name for the trade name drug, Adriamycin®, as well as, Rubex®, which is a type of anti-cancer chemotherapy drug called an anthracycline. Doxorubicin works by blocking an enzyme called TopoisomeraseⅡthat cancer cells need to divide and grow.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for ADC-1007-SHz. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "IgG Fc"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-548-F(E) | Recombinant Anti-IgG Fc Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| MHH-548-F(E) | Recombinant Human Anti-IgG Fc Antibody Fab Fragment | WB, Dot, FuncS | Fab |
| PFBZ-080 | Human Anti-IgG Fc Recombinant Antibody; Fab Fragment (PFBZ-080) | WB, IF, FuncS | Human Fab |
| FAMAB-0023JF-F(E) | Human Anti-IgG Fc Recombinant Antibody (clone A4); Fab Fragment | WB, FC, ELISA, FuncS | Human Fab |
| FAMAB-0024JF-F(E) | Human Anti-IgG Fc Recombinant Antibody (clone NA6); Fab Fragment | WB, FC, ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-548-S(P) | Recombinant Anti-IgG Fc Antibody scFv Fragment | WB, IF, FuncS | scFv |
| MHH-548-S(P) | Recombinant Human Anti-IgG Fc Antibody scFv Fragment | WB, ELISA, IHC, FuncS | scFv |
| PSBZ-080 | Human Anti-IgG Fc Recombinant Antibody; scFv Fragment (PSBZ-080) | WB, IF, FuncS | Human scFv |
| FAMAB-0023JF-S(P) | Human Anti-IgG Fc Recombinant Antibody (clone A4); scFv Fragment | WB, FC, ELISA, FuncS | Human scFv |
| FAMAB-0024JF-S(P) | Human Anti-IgG Fc Recombinant Antibody (clone NA6); scFv Fragment | WB, FC, ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-548 | Recombinant Human Anti-IgG Fc Antibody | IF, Neut, FuncS | IgG |
| PABZ-080 | Human Anti-IgG Fc Recombinant Antibody (PABZ-080) | WB, IF, FuncS | Human IgG |
| FAMAB-0023JF | Human Anti-IgG Fc Recombinant Antibody (clone A4) | ELISA, FuncS | Human IgM |
| FAMAB-0024JF | Human Anti-IgG Fc Recombinant Antibody (clone NA6) | ELISA, FuncS | Human IgM |
| VS-0224-XY85 | Goat Anti-Mouse IgG Fc Recombinant Antibody (VS-0224-XY85) | ELISA | Goat IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0356MC | FITC anti-Human IgG Fc Antibody | FC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: ELISA, SPR, Inhib, FuncS
Application: FC, FRET, Internalization
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA
Application: ELISA, PD, Activ, PK, Stim
-2.png)
Application: ELISA
Application: Neut, IHC, Activ, FuncS, IF, ELISA
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
