Recombinant Human Anti-WT1 Soluble TCR (C-Cys) (VS-0622-YF3183) (CAT#: VS-0622-YF3183)
Human TCR recognizes WT1 peptide (RMFPNAPYL) in the context of HLA-A2. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
Specific Inquiry
Specifications
- Host Species
- Human
- Target
- WT1
- Species Reactivity
- Human
- Epitope
- RMFPNAPYL
- MHC
- HLA-A2
- Type
- Soluble TCR (C-Cys)
- Related Disease
- Cancer
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
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