Recombinant Mouse Anti-IAPP Soluble TCR (BDC-5.2.9) (ZIP-Fos/ZIP-Jun)
CAT#: VS-0622-YF1022
Mouse TCR (BDC-5.2.9) recognizes IAPP peptide (KCNTATCATQRLANFLVRSS) in the context of HLA class II. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Mouse soluble TCR (BDC-5.2.9). Please note that the activity is not guaranteed.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/1947_F12_2_selected.jpg
Normal Tissue
Figure 2 High expression in pancreas
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3_val_selected.jpg
Normal Tissue
Figure 3 Low expression in colon
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_9_3_val_selected.jpg
Normal Tissue
Figure 4 Pancreas
Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (U-2 OS)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121351-IAPP
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Specifications
- Host Species
- Mouse
- Target
- IAPP
- Species Reactivity
- Mouse
- Epitope
- KCNTATCATQRLANFLVRSS
- MHC
- HLA class II
- Clone
- BDC-5.2.9
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Pancreatic cancer
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2254z | Mouse Anti-IAPP Recombinant Antibody (clone 35D9) | ICC, IF, IHC | Mouse IgG1 |
| HPAB-0295-YC | Human Anti-IAPP Recombinant Antibody (clone HlLl) | FuncS | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-375CL | Human Anti-IAPP Recombinant Antibody (TAB-375CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-118CT | Human Anti-IAPP Recombinant Antibody (TAB-118CT) | ELISA | Human IgG |
| TAB-119CT | Human Anti-IAPP Recombinant Antibody (TAB-119CT) | ELISA | Human IgG |
| TAB-120CT | Human Anti-IAPP Recombinant Antibody (TAB-120CT) | ELISA | Human IgG |
| TAB-118CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-118CT-S(P)) | ELISA | Human scFv |
| TAB-119CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-119CT-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC671 | PE-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-LC672 | APC-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-LC673 | BV421-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-YF299 | A*02:01/Human IAPP (KLQVFLIVL) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0295-YC-S(P) | Human Anti-IAPP Recombinant Antibody (clone HlLl); scFv Fragment | FuncS | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0295-YC-F(E) | Human Anti-IAPP Recombinant Antibody (clone HlLl); Fab Fragment | FuncS | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3366 | Anti-IAPP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC148 | Recombinant Anti-IAPP Eliminating Antibody, pH-Sensitive (VS-0625-YC148) | Antigen-Sweeping In Vivo. | Human IgG |
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