Rabbit Anti-Lyn (phospho Y396) Monoclonal Antibody
CAT#: VS-0126-XL221
Targeting the active Tyrosine 396 residue of the Lyn kinase, this rabbit-sourced monoclonal ensures accurate protein localization. It is a specialized tool for studying Src-family signaling specifically validated for WB.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1231/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human spleen
High expression. RNA expression: 85.4 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1231/4032_B_7_4_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human cerebral cortex
Low expression. RNA expression: 8.7 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1231/4032_B_8_5_val_selected.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1231/4032_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4492/12394_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1231/4032_A_9_5.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1231/4032_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (HEL, HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000254087-LYN
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Specifications
- Host Species
- Rabbit
- Antibody Isotype
- Rabbit IgG
- Specificity
- Lyn (phospho Y396)
- Species Reactivity
- Human; Mouse
- Applications
- WB
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Derived from a sophisticated chromatographic separation process that utilizes specific affinity ligands for the rapid isolation of the target antibody.
- Concentration
- Lot specific
- Storage
- Store at -20˚C
- Shipping
- Ice Packs
Applications
- Application Notes
- WB: 1:500-1:2000
Target
- Alternative Names
- Tyrosine-protein kinase Lyn; JTK8; p53Lyn; p56Lyn
- UniProt ID
- P07948
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Related Signaling Pathways
BCR Signaling Pathway
FcεR1 Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "LYN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2781z | Mouse Anti-LYN Recombinant Antibody (clone 33H4) | WB, ICC, IF, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1024MZ | Recombinant Mouse Anti-Human LYN Antibody (clone 3I9E8) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2108 | Hi-Affi™ Recombinant Rabbit Anti-LYN Monoclonal Antibody (DS2108AB) | IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-030R | Mouse Anti-Lyn Recombinant Antibody (ZG-030R) | WB, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX704 | Mouse Anti-LYN Recombinant Antibody (clone 1C8-H3-G6) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX705 | Mouse Anti-LYN Recombinant Antibody (clone 1174CT22.3.1.1) | WB | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY312 | Rabbit Anti-NHP LYN Recombinant Antibody (clone R.677.10) | WB, IHC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1279 | Anti-LYN Immunohistochemistry Kit | IHC |
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