This ADC product is composed of a Fab fragment of an anti-rat IgG Fc specific polyclonal antibody conjugated via a non-cleavable linker to MMAF (anti-rat IgG(Fc)Fab-NC-MMAF). The antibody portion is a Fab fragment of a secondary antibody and the drug portion, MMAF, is a cytotoxic small molecule which inhibits cell division by depolymerizing microtubules. This product displays no obvious toxicity without a primary antibody and can be a quite efficient and economical alternative to pre-screening rat monoclonal antibodies as ADC candidates.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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