Recombinant Anti-AGER Vesicular Antibody, EV Displayed (VS-0425-YC640)
CAT#: VS-0425-YC640
The Recombinant Anti-AGER Vesicular Antibody, EV Displayed (VS-0425-YC640) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to AGER-expressed cells or tissues. AGER is a glycosylation end product receptor, interacting with various molecules linked to diseases like diabetes and Alzheimer's.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoli fibrillar center & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/64436/1232_G12_3_selected.jpg
Normal Tissue
Figure 2 Lung
Alveolar cells type I
Staining: High
Intensity: Strong
Quantity:>75%
Alveolar cells type II
Staining: Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69474/168057_A_2_4.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (HEK93, JURKAT, RPTEC TERT1, U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204305-AGER
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- AGER
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Advanced glycosylation end-product specific receptor
- Biological Process
- Inflammatory response
- Cellular Localization
- Plasma membrane, Cell Junctions, Nucleoli fibrillar center
- Introduction
- The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]
- Alternative Names
- RAGE, SCARJ1, sRAGE
- Gene ID
- 177
- UniProt ID
- Q15109
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC640. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "AGER"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-44-F(E) | Recombinant Anti-human AGER Antibody Fab Fragment | ELISA, Nert, FuncS | Fab |
| MHH-44-F(E) | Recombinant Human Anti-human AGER Antibody Fab Fragment | ELISA, WB, Dot, FuncS | Fab |
| HPAB-0086-YC-F(E) | Mouse Anti-AGER Recombinant Antibody Fab Fragment (HPAB-0086-YC-F(E)) | ELISA, RIA, IHC, Neut | Mouse Fab |
| HPAB-N0016-YC-F(E) | Human Anti-AGER Recombinant Antibody; Fab Fragment (HPAB-N0016-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-0341-FY-F(E) | Mouse Anti-AGER Recombinant Antibody Fab Fragment (HPAB-0341-FY-F(E)) | WB, IHC, ELISA, FC | Mouse Fab, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-44-S(P) | Recombinant Anti-human AGER Antibody scFv Fragment | WB, IP, FuncS | scFv |
| MHH-44-S(P) | Recombinant Human Anti-human AGER Antibody scFv Fragment | ELISA, WB, Neut, FuncS | scFv |
| HPAB-1476-FY-F(E) | Mouse Anti-AGER Recombinant Antibody; Fab Fragment (HPAB-1476-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-1477-FY-F(E) | Mouse Anti-AGER Recombinant Antibody; Fab Fragment (HPAB-1477-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-1478-FY-F(E) | Mouse Anti-AGER Recombinant Antibody; Fab Fragment (HPAB-1478-FY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-067 | Recombinant Anti-human AGER VHH Single Domain Antibody | WB, ELISA, IP, FC, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-44 | Recombinant Human Anti-human AGER Antibody | ELISA, WB, IP, FuncS | IgG |
| MOB-1390CT | Mouse Anti-AGER Recombinant Antibody (clone EML133) | FC, IHC-P, WB | Mouse IgG2a |
| HPAB-0086-YC | Mouse Anti-AGER Recombinant Antibody (HPAB-0086-YC) | ELISA, RIA, IHC, Neut | Mouse IgG |
| VS3-FY45 | Recombinant Rabbit Anti-AGER Antibody (clone R06-2H4) | WB | Rabbit IgG |
| VS3-WK1912 | Recombinant Rabbit Anti-Rat AGER Capture Antibody (clone R45-9J-5) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-293CT | Anti-Human RAGE Recombinant Antibody (XT-M4) | WB, ELISA, Neut, PK | Humanized antibody |
| TAB-293CT-S(P) | Anti-Human RAGE Recombinant Antibody scFv Fragment (XT-M4) | SPR, IF, FC, WB, ELISA, Neut | Humanized antibody |
| TAB-293CT-F(E) | Anti-Human RAGE Recombinant Antibody Fab Fragment (XT-M4) | WB, ELISA, Neut | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-294CT | Mouse Anti-AGER Recombinant Antibody (TAB-294CT) | WB, ELISA, Neut | Mouse IgG |
| TAB-295CT | Mouse Anti-AGER Recombinant Antibody (TAB-295CT) | WB, ELISA, Neut | Mouse IgG |
| TAB-296CT | Mouse Anti-AGER Recombinant Antibody (TAB-296CT) | ELISA | Mouse IgG |
| TAB-297CT | Mouse Anti-AGER Recombinant Antibody (TAB-297CT) | ELISA | Mouse IgG |
| TAB-298CT | Mouse Anti-AGER Recombinant Antibody (TAB-298CT) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-016CQ | Mouse Anti-AGER Recombinant Antibody (NEUT-016CQ) | WB, Neut | Mouse IgG2 |
| NEUT-017CQ | Mouse Anti-AGER Recombinant Antibody (clone CBL155) | Neut, WB | Mouse IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-018CQ | Mouse Anti-AGER Recombinant Antibody (clone CBL401) | Block, WB, ELISA | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0100 | Hi-Affi™ Rabbit Anti-AGER Recombinant Antibody (clone DS100AB) | WB | Rabbit IgG |
| MOR-4724 | Hi-Affi™ Rabbit Anti-AGER Recombinant Antibody (clone TH238DS) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY56 | Anti-AGER Immunohistochemistry Kit | IHC | |
| VS-0525-XY210 | Anti-Mouse Ager Immunohistochemistry Kit | IHC | |
| VS-0525-XY209 | Anti-Human AGER Immunohistochemistry Kit | IHC | |
| VS-0525-XY211 | Anti-Rat AGER Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC31 | CytoStream™ Rabbit Anti-Ager Polyclonal Antibody (VS13-YC31) | WB, IHC-P, FC | Rabbit IgG |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application:
Application: WB, ELISA, FuncS, Inhib, PK, IP, SPR
Application: ELISA, FuncS
Application: ELISA, FC, Neut, Inhib
-2.png)
Application: ELISA
Application: ELISA, Activ, Block
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
