Recombinant Anti-AGER Vesicular Antibody, EV Displayed (VS-0425-YC640) (CAT#: VS-0425-YC640)

• Application
• ELISA, FC, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• AGER

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Mouse

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Advanced glycosylation end-product specific receptor

• Biological Process
• Inflammatory response

• Cellular Localization
• Plasma membrane, Cell Junctions, Nucleoli fibrillar center

• Introduction
• The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]

• Alternative Names
• RAGE, SCARJ1, sRAGE

• Gene ID
• 177

• UniProt ID
• Q15109

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