Recombinant Human Anti-human AGER Antibody (CAT#: MHH-44)
Recombinant Human Antibody shows strong binding capacity to Human AGER, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-AGER mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-AGER mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Custom Production
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoli fibrillar center & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64436/1232_G12_3_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoli fibrillar center & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64436/1232_G12_3_selected.jpg
Figure 2 Lung
(Alveolar cells type I
Staining: High
Intensity: Strong
Quantity:>75%
Alveolar cells type II
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69474/168057_A_2_4.jpg
(Alveolar cells type I
Staining: High
Intensity: Strong
Quantity:>75%
Alveolar cells type II
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69474/168057_A_2_4.jpg
Figure 3 RNA cell line category: Cell line enhanced (HEK93, JURKAT, RPTEC TERT1, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204305-AGER
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204305-AGER
Specifications
- Immunogen
- Human advanced glycosylation end product-specific receptor
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human advanced glycosylation end product-specific receptor
- Species Reactivity
- Human
- Applications
- Products can be used for: Enzyme-linked Immunosorbent Assay; Western blot; Immunoprecipitation; Functional Study
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- AGER; advanced glycosylation end product-specific receptor; RAGE; RAGE isoform sRAGE-delta; RAGE isoform NtRAGE-delta; receptor for advanced glycation end-products variant 20
- Gene ID
- 177
- UniProt ID
- B4DNX3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-44-S(P) | Recombinant Anti-human AGER Antibody scFv Fragment | WB, IP, FuncS | scFv |
| HPAB-N0016-YC-S(P) | Human Anti-AGER Recombinant Antibody; scFv Fragment (HPAB-N0016-YC-S(P)) | ELISA | Human scFv |
| HPAB-1476-FY-F(E) | Mouse Anti-AGER Recombinant Antibody; Fab Fragment (HPAB-1476-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-1477-FY-F(E) | Mouse Anti-AGER Recombinant Antibody; Fab Fragment (HPAB-1477-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-1478-FY-F(E) | Mouse Anti-AGER Recombinant Antibody; Fab Fragment (HPAB-1478-FY-F(E)) | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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