Recombinant Anti-BDNF Vesicular Antibody, EV Displayed (VS-0425-YC576) (CAT#: VS-0425-YC576)

• Application
• ELISA, FC, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• BDNF

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Brain derived neurotrophic factor

• Molecular Function
• Growth factor

• Introduction
• This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]

• Gene ID
• 627

• UniProt ID
• P23560

Select a product category from the dropdown menu below to view related products.