Mouse Anti-BDNF Recombinant Antibody (clone CBL263) (CAT#: NEUT-044CQ)
This antibody is a mouse monoclonal antibody that binds specifically to BDNF, and it can neutralize the bioactivity of BDNF.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31440/1056_B9_4_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31440/1056_B9_4_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9564/162501_B_7_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9564/162501_B_7_5.jpg
Figure 3 Cerebellum
(GLUC cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Granular cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Molecular layer cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Molecular layer cells - nucleus
Staining: Medium
Intensity: Moderate
Processes in molecular layer
Staining: Medium
Intensity: Moderate
Synaptic glomeruli - core
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9564/162501_B_8_8.jpg
(GLUC cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Granular cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Molecular layer cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Molecular layer cells - nucleus
Staining: Medium
Intensity: Moderate
Processes in molecular layer
Staining: Medium
Intensity: Moderate
Synaptic glomeruli - core
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9564/162501_B_8_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, HBF TERT88, U-138 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000176697-BDNF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000176697-BDNF
Specifications
- Immunogen
- Recombinant protein corresponding to 119aa from purified human brain BDNF (13.6kD)
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Recognizes human BDNF
- Species Reactivity
- Human
- Clone
- CBL263
- Applications
- ELISA, WB, Neut
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified by affinity chromatography
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Cocaine Addiction
Alcoholism
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-107 | Recombinant Anti-human BDNF Antibody | ELISA, WB, Dot, FuncS | IgG |
| MOB-0467MZ | Mouse Anti-BDNF Recombinant Antibody (clone 46039.22) | ELISA, IHC-P, WB | Mouse IgG1 |
| MRO-1686-CN | Rabbit Anti-BDNF Polyclonal Antibody (MRO-1686-CN) | WB, IF, IHC | Rabbit IgG |
| HPAB-0351-FY | Human Anti-BDNF Recombinant Antibody (clone R3BH1) | ELISA, Inhib, FuncS, Neut | Chimeric (chicken/human) IgG1, λ |
| VS3-XY120 | Mouse Anti-BDNF Recombinant Antibody (clone 3D9C5) | ELISA, WB, ICC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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