Chicken Anti-BDNF Recombinant Antibody (clone R3BH1); scFv Fragment (CAT#: HPAB-0351-FY-S(P))
Recombinant scFv fragment to BDNF. This product is a recombinant antibody that recognizes Human BDNF. The monoclonal antibody R3BH1 reacts with the epitope (C-terminus) of BDNF. Anti-BDNF antibody R3BH1 and TrkB-Fc molecule inhibits TrkB receptor activation and downstream signalling mediated by BDNF, as measured by phosphorylated pERK activity.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31440/1056_B9_4_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31440/1056_B9_4_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9564/162501_B_7_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9564/162501_B_7_5.jpg
Figure 3 Cerebellum
(GLUC cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Granular cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Molecular layer cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Molecular layer cells - nucleus
Staining: Medium
Intensity: Moderate
Processes in molecular layer
Staining: Medium
Intensity: Moderate
Synaptic glomeruli - core
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9564/162501_B_8_8.jpg
(GLUC cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Granular cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Molecular layer cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Molecular layer cells - nucleus
Staining: Medium
Intensity: Moderate
Processes in molecular layer
Staining: Medium
Intensity: Moderate
Synaptic glomeruli - core
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9564/162501_B_8_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, HBF TERT88, U-138 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000176697-BDNF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000176697-BDNF
Specifications
- Host Species
- Chicken
- Type
- Chicken scFv
- Specificity
- Human BDNF
- Species Reactivity
- Human
- Clone
- R3BH1
- Applications
- Block
- Related Disease
- Parkinson's disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Brain Derived Neurotrophic Factor; Neurotrophin; Abrineurin; Brain-Derived Neurotrophic Factor; ANON2; BULN2;
- Gene ID
- 627
- UniProt ID
- P23560
Related Resources
Cocaine Addiction
Alcoholism
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Humanized Antibody Products
Chicken IgY Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-107 | Recombinant Anti-human BDNF Antibody | ELISA, WB, Dot, FuncS | IgG |
| MHH-107 | Recombinant Human Anti-human BDNF Antibody | ELISA, WB, FuncS | IgG |
| MOB-0467MZ | Mouse Anti-BDNF Recombinant Antibody (clone 46039.22) | ELISA, IHC-P, WB | Mouse IgG1 |
| MRO-0166-CN | Rabbit Anti-BDNF Recombinant Antibody (clone CBACN-065) | WB, IHC, IF | Rabbit IgG |
| MRO-1686-CN | Rabbit Anti-BDNF Polyclonal Antibody (MRO-1686-CN) | WB, IF, IHC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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