Chicken Anti-BDNF Recombinant Antibody (clone R3BH1); scFv Fragment
CAT#: HPAB-0351-FY-S(P)
Recombinant scFv fragment to BDNF. This product is a recombinant antibody that recognizes Human BDNF. The monoclonal antibody R3BH1 reacts with the epitope (C-terminus) of BDNF. Anti-BDNF antibody R3BH1 and TrkB-Fc molecule inhibits TrkB receptor activation and downstream signalling mediated by BDNF, as measured by phosphorylated pERK activity.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31440/1056_B9_4_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9564/162501_B_7_5.jpg
Normal Tissue
Figure 3 Cerebellum
GLUC cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Granular cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Molecular layer cells - cytoplasm/membrane
Staining: Medium
Intensity: Moderate
Molecular layer cells - nucleus
Staining: Medium
Intensity: Moderate
Processes in molecular layer
Staining: Medium
Intensity: Moderate
Synaptic glomeruli - core
Staining: Medium
Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9564/162501_B_8_8.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, HBF TERT88, U-138 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000176697-BDNF
❮
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Specifications
- Host Species
- Chicken
- Type
- Chicken scFv
- Specificity
- Human BDNF
- Species Reactivity
- Human
- Clone
- R3BH1
- Applications
- Block
- Related Disease
- Parkinson's disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Related Diseases
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Alcoholism
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone R3BH1"
- CAT
- Product Name
See other products for "BDNF"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-107 | Recombinant Anti-human BDNF Antibody | ELISA, WB, Dot, FuncS | IgG |
| MHH-107 | Recombinant Human Anti-human BDNF Antibody | ELISA, WB, FuncS | IgG |
| MOB-0467MZ | Mouse Anti-BDNF Recombinant Antibody (clone 46039.22) | ELISA, IHC-P, WB | Mouse IgG1 |
| MRO-0166-CN | Rabbit Anti-BDNF Recombinant Antibody (clone CBACN-065) | WB, IHC, IF | Rabbit IgG |
| MRO-1686-CN | Rabbit Anti-BDNF Polyclonal Antibody (MRO-1686-CN) | WB, IF, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-107-F(E) | Recombinant Anti-human BDNF Antibody Fab Fragment | ELISA, IP, FuncS | Fab |
| MHH-107-F(E) | Recombinant Human Anti-human BDNF Antibody Fab Fragment | ELISA, WB, Neut, FuncS | Fab |
| HPAB-0351-FY-F(E) | Human Anti-BDNF Recombinant Antibody (clone R3BH1); Fab Fragment | Block | Chimeric (chicken/human) Fab, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-107-S(P) | Recombinant Anti-human BDNF Antibody scFv Fragment | FC, RIA, Biosensors, FuncS | scFv |
| MHH-107-S(P) | Recombinant Human Anti-human BDNF Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1247CL-S(P) | Anti-Human BDNF Recombinant Antibody scFv Fragment (B30) | Inhib, FuncS | Humanized antibody |
| TAB-1248CL-S(P) | Anti-Human BDNF Recombinant Antibody scFv Fragment (B20) | ELISA, Inhib | Humanized antibody |
| TAB-1249CL-S(P) | Anti-Human BDNF Recombinant Antibody scFv Fragment (B18) | ELISA, Inhib | Humanized antibody |
| TAB-1247CL-F(E) | Anti-Human BDNF Recombinant Antibody Fab Fragment (B30) | Inhib, FuncS | Humanized antibody |
| TAB-1248CL-F(E) | Anti-Human BDNF Recombinant Antibody Fab Fragment (B20) | ELISA, Inhib | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0825MZ | Chicken Anti-BDNF Polyclonal IgY | ELISA | Chicken antibody |
| BRD-1149MZ | Chicken Anti-Human BDNF Polyclonal IgY | ELISA | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-044CQ | Mouse Anti-BDNF Recombinant Antibody (clone CBL263) | ELISA, WB, Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0351 | Hi-Affi™ Rabbit Anti-BDNF Recombinant Antibody (clone DS351AB) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC576 | Recombinant Anti-BDNF Vesicular Antibody, EV Displayed (VS-0425-YC576) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY753 | Anti-BDNF Immunohistochemistry Kit | IHC | |
| VS-0525-XY754 | Anti-Mouse BDNF Immunohistochemistry Kit | IHC |
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